Department of Medical Psychology and Medical Sociology, Georg-August-University, Goettingen, Germany.
J Neurotrauma. 2010 Jul;27(7):1167-85. doi: 10.1089/neu.2009.1076.
The consequences of traumatic brain injury (TBI) for health-related quality of life (HRQoL) are poorly investigated, and a TBI-specific instrument has not previously been available. The cross-cultural development of a new measure to assess HRQoL after TBI is described here. An international TBI Task Force derived a conceptual model from previous work, constructed an initial item bank of 148 items, and then reduced the item set through two successive multicenter validation studies. The first study, with eight language versions of the QOLIBRI, recruited 1528 participants with TBI, and the second with six language versions, recruited 921 participants. The data from 795 participants from the second study who had complete Glasgow Coma Scale (GCS) and Glasgow Outcome Scale (GOS) data were used to finalize the instrument. The final version of the QOLIBRI consists of 37 items in six scales (see Appendix ). Satisfaction is assessed in the areas of "Cognition," "Self," "Daily Life and Autonomy," and "Social Relationships," and feeling bothered by "Emotions," and "Physical Problems." The QOLIBRI scales meet standard psychometric criteria (internal consistency, alpha = 0.75-0.89, test-retest reliability, r(tt) = 0.78-0.85). Test-retest reliability (r(tt) = 0.68-0.87) as well as internal consistency (alpha = 0.81-0.91) were also good in a subgroup of participants with lower cognitive performance. Although there is one strong HRQoL factor, a six-scale structure explaining additional variance was validated by exploratory and confirmatory factor analyses, and with Rasch modeling. The QOLIBRI is a new cross-culturally developed instrument for assessing HRQoL after TBI that fulfills standard psychometric criteria. It is potentially useful for clinicians and researchers conducting clinical trials, for assessing the impact of rehabilitation or other interventions, and for carrying out epidemiological surveys.
创伤性脑损伤 (TBI) 对健康相关生活质量 (HRQoL) 的影响研究甚少，并且之前没有专门用于 TBI 的工具。本文介绍了一种新的 TBI 后 HRQoL 评估工具的跨文化开发。一个国际 TBI 工作组从之前的工作中得出了一个概念模型，构建了一个包含 148 项初始项目的初始项目库，然后通过两项连续的多中心验证研究对项目集进行了简化。第一项研究有 8 种语言版本的 QOLIBRI，共招募了 1528 名 TBI 参与者，第二项研究有 6 种语言版本，共招募了 921 名参与者。第二项研究中有 795 名参与者完成了格拉斯哥昏迷量表 (GCS) 和格拉斯哥结果量表 (GOS) 数据，这些数据用于最终确定工具。QOLIBRI 的最终版本包含六个量表中的 37 个项目（见附录）。在“认知”、“自我”、“日常生活和自主”和“社会关系”领域评估满意度，并评估“情绪”和“身体问题”的困扰程度。QOLIBRI 量表符合标准心理计量学标准（内部一致性，α=0.75-0.89，重测信度，r(tt)=0.78-0.85）。在认知表现较低的参与者亚组中，重测信度（r(tt)=0.68-0.87）和内部一致性（α=0.81-0.91）也很好。探索性和验证性因子分析以及 Rasch 建模也验证了一个包含额外方差的六尺度结构。QOLIBRI 是一种新的跨文化开发的 TBI 后 HRQoL 评估工具，符合标准心理计量学标准。它对进行临床试验的临床医生和研究人员、评估康复或其他干预措施的影响以及进行流行病学调查可能很有用。
