1Department of Psychiatry, Crozer Chester Medical Center, One Medical Center Boulevard, Upland, PA, USA.
Am J Alzheimers Dis Other Demen. 2013 Dec;28(8):776-83. doi: 10.1177/1533317513504817.
To determine whether subjective memory complaints (SMCs) are associated with performance on objective cognitive measures and psychological factors in healthy, community-dwelling older adults.
The cohort was composed of adults, 65 years and older with no clinical evidence of cognitive impairment (n = 125). Participants were administered: CogState computerized neurocognitive battery, Prospective Retrospective Memory Questionnaire, personality and meaning-in-life measures.
SMCs were associated with poorer performance on measures of executive function (p = 0.001). SMCs were also associated with impaired delayed recall (p = 0.006) but this did not remain significant after statistical adjustment for multiple comparisons. SMCs were inversely associated with conscientiousness (p = 0.004) and directly associated with neuroticism (p < 0.001). Higher scores on SMCs were associated with higher perceived stress (p = 0.001), and ineffective coping styles (p = 0.001). Factors contributing to meaning-in-life were associated with fewer SMCs (p < 0.05).
SMCs may reflect early, subtle cognitive changes and are associated with personality traits and meaning-in-life in healthy, older adults.
确定主观记忆抱怨(SMC)是否与健康的、居住在社区的老年人的客观认知测量和心理因素相关。
该队列由无认知障碍临床证据的 65 岁及以上成年人组成(n=125)。参与者接受了:CogState 计算机化神经认知测试、前瞻性回顾记忆问卷、人格和生活意义测量。
SMC 与执行功能测量上的较差表现相关(p=0.001)。SMC 也与延迟回忆受损相关(p=0.006),但在进行多次比较的统计调整后,这种相关性不再显著。SMC 与尽责性呈负相关(p=0.004),与神经质呈正相关(p<0.001)。SMC 得分较高与感知压力较高(p=0.001)和无效应对方式(p=0.001)相关。对生活意义有贡献的因素与较少的 SMC 相关(p<0.05)。
SMC 可能反映了早期、微妙的认知变化,与健康老年人的人格特质和生活意义相关。