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兵库离子线医疗中心的带电粒子线治疗:特征、技术和临床结果。

Charged particle radiotherapy at the Hyogo Ion Beam Medical Center: Characteristics, technology and clinical results.

机构信息

Honorary Adviser, Hyogo Ion Beam Medical Center. ; Professor Emeritus, Kyoto University.

出版信息

Proc Jpn Acad Ser B Phys Biol Sci. 2007 Sep;83(6):151-63. doi: 10.2183/pjab.83.151.

DOI:10.2183/pjab.83.151
PMID:24367141
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3855203/
Abstract

The Hyogo Ion Beam Medical Center was constructed in 2001 as the world's first charged particle radiotherapy center where both proton and carbon-ion radiotherapy can be performed. From April 2001 to February 2007, more than 1,400 patients with a variety of cancers were treated. Most of the tumors except for prostate cancer were considered hard to cure with standard treatments such as surgery or conventional x-ray radiotherapy. The clinical results obtained so far are very encouraging, mainly due to the excellent dose localization to the tumor and strong cell killing effects of protons and carbon-ions. The good indications are localized tumors including skull base tumors, head and neck tumors, cancers of the lung, the liver, and the prostate, and bone and soft tissue sarcomas. Charged particle radiotherapy will significantly improve the quality of life of cancer patients and promote their speedy return to normal lives or work if it is used for early stage cancer.

摘要

兵库离子束医疗中心于 2001 年建成,是世界上首个能够同时进行质子和碳离子放疗的重离子放疗中心。自 2001 年 4 月至 2007 年 2 月,已有 1400 多名患有各种癌症的患者接受了治疗。除前列腺癌外,大多数肿瘤都被认为难以通过手术或常规 X 射线放疗等标准治疗方法治愈。迄今为止获得的临床结果非常令人鼓舞,主要是由于质子和碳离子具有出色的肿瘤定位和强大的细胞杀伤作用。适应证为局限性肿瘤,包括颅底肿瘤、头颈部肿瘤、肺癌、肝癌和前列腺癌,以及骨和软组织肉瘤。如果将重离子放疗用于早期癌症,将显著提高癌症患者的生活质量,并促进他们尽快恢复正常生活或工作。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8448/3855203/e300f18f3689/83_151f9.jpg
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