Dalal Priti G, Bosak Jodi, Berlin Cheston
Department of Anesthesiology, Penn State University College of Medicine, Milton S Hershey Medical Center, Hershey, PA, USA.
Paediatr Anaesth. 2014 Apr;24(4):359-71. doi: 10.1111/pan.12331. Epub 2013 Dec 24.
There has been an increase in breast-feeding supported by the recommendations of the American Academy of Pediatrics and the World Health Organization. An anesthesiologist may be presented with a well-motivated breast-feeding mother who wishes to breast-feed her infant in the perioperative period. Administration of anesthesia entails acute administration of drugs with potential for sedation and respiratory effects on the nursing infant. The short-term use of these drugs minimizes the possibility of these effects. The aim should be to minimize the use of narcotics and benzodiazepines, use shorter acting agents, use regional anesthesia where possible and avoid agents with active metabolites. Frequent clinical assessments of the nursing infant are important. Available literature does suggest that although the currently available anesthetic and analgesic drugs are transferred in the breast milk, the amounts transferred are almost always clinically insignificant and pose little or no risk to the nursing infant.
在美国儿科学会和世界卫生组织建议的支持下,母乳喂养的情况有所增加。麻醉医生可能会遇到一位积极性很高的母乳喂养母亲,她希望在围手术期给婴儿喂奶。麻醉给药需要急性给予可能对哺乳婴儿产生镇静和呼吸作用的药物。这些药物的短期使用可将这些影响的可能性降至最低。目标应该是尽量减少麻醉药品和苯二氮䓬类药物的使用,使用作用时间较短的药物,尽可能使用区域麻醉,并避免使用有活性代谢物的药物。对哺乳婴儿进行频繁的临床评估很重要。现有文献确实表明,尽管目前可用的麻醉和镇痛药物会进入母乳,但进入母乳的量几乎在临床上都无足轻重,对哺乳婴儿几乎不构成风险或没有风险。