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Transl Perioper Pain Med. 2015;1(2):1-7.
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本文引用的文献

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Response to Silvani and Camporesi, regarding their comment on our paper Safety of the breast-feeding infant after maternal anesthesia.
Paediatr Anaesth. 2014 Apr;24(4):453-4. doi: 10.1111/pan.12376.
2
[Anesthesia and analgesia in the lactation period. Criteria for drug selection].[哺乳期的麻醉与镇痛。药物选择标准]
Anaesthesist. 2014 May;63(5):415-21. doi: 10.1007/s00101-014-2311-1.
3
Safety of the breast-feeding infant after maternal anesthesia.母亲麻醉后母乳喂养婴儿的安全性。
Paediatr Anaesth. 2014 Apr;24(4):359-71. doi: 10.1111/pan.12331. Epub 2013 Dec 24.
4
A randomized controlled trial of the efficacy and respiratory effects of patient-controlled intravenous remifentanil analgesia and patient-controlled epidural analgesia in laboring women.一项随机对照试验研究了产妇自控静脉注射瑞芬太尼镇痛和自控硬膜外镇痛的疗效和呼吸影响。
Anesth Analg. 2014 Mar;118(3):589-97. doi: 10.1213/ANE.0b013e3182a7cd1b.
5
Contribution of protein binding, lipid partitioning, and asymmetrical transport to drug transfer into milk in mouse versus human.蛋白质结合、脂相分配和不对称转运对药物向人和鼠乳汁中转移的贡献。
Pharm Res. 2013 Sep;30(9):2410-22. doi: 10.1007/s11095-013-1085-5. Epub 2013 May 31.
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Breastfeeding after anaesthesia: a review of the pharmacological impact on children.麻醉后母乳喂养:对儿童药理影响的综述
Anaesth Intensive Care. 2013 Jan;41(1):35-40. doi: 10.1177/0310057X1304100107.
7
ABM clinical protocol #15: analgesia and anesthesia for the breastfeeding mother, revised 2012.ABM 临床实践规程 #15:母乳喂养母亲的镇痛与麻醉,2012 年修订版。
Breastfeed Med. 2012 Dec;7(6):547-53. doi: 10.1089/bfm.2012.9977.
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Breastfeeding and the use of human milk.母乳喂养与人类乳汁使用。
Pediatrics. 2012 Mar;129(3):e827-41. doi: 10.1542/peds.2011-3552. Epub 2012 Feb 27.
9
"Breast is best": The evidence.“母乳喂养最好”:证据。
Early Hum Dev. 2010 Nov;86(11):729-32. doi: 10.1016/j.earlhumdev.2010.08.005. Epub 2010 Sep 16.
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[Course and treatment of myasthenia gravis during pregnancy].[重症肌无力在孕期的病程及治疗]
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麻醉后母乳喂养:麻醉医护人员关于药物向母乳中转移的综述

Breastfeeding after Anesthesia: A Review for Anesthesia Providers Regarding the Transfer of Medications into Breast Milk.

作者信息

Cobb Benjamin, Liu Renyu, Valentine Elizabeth, Onuoha Onyi

机构信息

Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania.

出版信息

Transl Perioper Pain Med. 2015;1(2):1-7.

PMID:26413558
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4582419/
Abstract

Doctors, nurses, and midwives often inform mothers to "pump and dump" their breast milk for 24 hours after receiving anesthesia to avoid passing medications to the infant. This advice, though cautious, is probably outdated. This review highlights the more recent literature regarding common anesthesia medications, their passage into breast milk, and medication effects observed in breastfed infants. We suggest continuing breastfeeding after anesthesia when the mother is awake, alert, and able to hold her infant. We recommend multiple types of medications for pain relief while minimizing sedating medications. Few medications can have sedating effects to the infant, but those medications are specifically outlined. For additional safety, anesthesia providers and patients may screen medications using the National Institute of Health' LactMed database.

摘要

医生、护士和助产士通常会告知母亲,在接受麻醉后要“挤掉并丢弃”母乳24小时,以避免将药物传递给婴儿。这条建议虽然谨慎,但可能已经过时。这篇综述着重介绍了关于常见麻醉药物、它们进入母乳的情况以及在母乳喂养婴儿中观察到的药物作用的最新文献。我们建议,当母亲清醒、警觉且能够抱持婴儿时,麻醉后可继续母乳喂养。我们推荐使用多种药物来缓解疼痛,同时尽量减少镇静药物的使用。很少有药物会对婴儿产生镇静作用,但那些药物会被具体列出。为了更高的安全性,麻醉医生和患者可以使用美国国立卫生研究院的LactMed数据库来筛选药物。