洋葱（干鳞茎）对革兰氏阳性菌、革兰氏阴性菌和真菌的体外抗菌活性。

In Vitro antimicrobial activity of Allium cepa (dry bulbs) against Gram positive and Gram negative bacteria and fungi.

作者信息

Bakht Jehan, Khan Shehla, Shafi Mohammad

机构信息

Institute of Biotechnology and Genetic Engineering, The University of Agriculture, Peshawar, KPK, Pakistan.

Department of Agronomy, The University of Agriculture, Peshawar, KPK, Pakistan.

出版信息

Pak J Pharm Sci. 2014 Jan;27(1):139-45.

PMID:24374441

Abstract

The present research was carried out at the Institute of Biotechnology and Genetic Engineering, the University of Agriculture Peshawar KPK Pakistan. Analysis of the data revealed that all the extracts from dry bulbs showed different ranges of antimicrobial activities. Ethyl acetate fractions showed inhibitory activities against all tested eight microbes including bacteria and a fungus while chloroform fractions inhibited all the microbes except Pseudomonas aeruginosa. Butanol fractions showed second highest activity at both lower and higher concentrations. Ethanol and water fractions were found least effective or ineffective. Among Gram positive microbes, Staphylococcus aureus was the most susceptible bacteria and the most resistant Gram negative bacteria were Pseudomonas aeurginosa and Salmonella typhi.

摘要

本研究在巴基斯坦开伯尔-普赫图赫瓦省白沙瓦农业大学的生物技术与基因工程研究所进行。数据分析表明，干鳞茎的所有提取物均表现出不同程度的抗菌活性。乙酸乙酯馏分对包括细菌和一种真菌在内的所有八种受试微生物均有抑制活性，而氯仿馏分除铜绿假单胞菌外抑制了所有微生物。丁醇馏分在低浓度和高浓度下均表现出第二高的活性。乙醇和水馏分被发现效果最差或无效果。在革兰氏阳性微生物中，金黄色葡萄球菌是最敏感的细菌，而最具抗性的革兰氏阴性细菌是铜绿假单胞菌和伤寒沙门氏菌。