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新型隐球菌:从历史奇闻到现代病原体

Cryptococcus neoformans: historical curiosity to modern pathogen.

作者信息

Srikanta Deepa, Santiago-Tirado Felipe H, Doering Tamara L

机构信息

Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO, USA.

出版信息

Yeast. 2014 Feb;31(2):47-60. doi: 10.1002/yea.2997. Epub 2014 Jan 19.

Abstract

The importance of the Basidiomycete Cryptococcus neoformans to human health has stimulated its development as an experimental model for both basic physiology and pathogenesis. We briefly review the history of this fascinating and versatile fungus, some notable aspects of its biology that contribute to virulence, and current tools available for its study.

摘要

担子菌新生隐球菌对人类健康的重要性推动了它成为基础生理学和发病机制研究的实验模型。我们简要回顾一下这种迷人且多功能真菌的历史、其生物学中一些导致毒力的显著方面以及目前可用于研究它的工具。

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