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一例眼眶隐球菌病。

A case of orbital cryptococcosis.

作者信息

Afkhamnejad Elahhe Rebecca, Turner Catherine, Reynoso David

机构信息

Department of Ophthalmology and Visual Sciences, University of Texas Medical Branch, 700 University Blvd, Galveston, TX, 77550, USA.

Department of Internal Medicine, Division of Infectious Diseases, University of Texas Medical Branch, 301 University Boulevard, Galveston, TX, 77555, USA.

出版信息

Am J Ophthalmol Case Rep. 2023 Feb 19;30:101821. doi: 10.1016/j.ajoc.2023.101821. eCollection 2023 Jun.

DOI:10.1016/j.ajoc.2023.101821
PMID:36852304
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9958422/
Abstract

PURPOSE

This report describes a case of found in an unlikely location, the orbit, in an apparently immunocompetent host.

OBSERVATIONS

A coordinated, multi-disciplinary approach between the ophthalmology, neurosurgery, pathology, and infectious disease departments was integral to saving both vision and life.

CONCLUSIONS AND IMPORTANCE

This is the first case of primary orbital cryptococcosis described in the medical literature, to the authors' knowledge. The case draws attention to the possibility that can indeed invade the orbit and should be considered part of the differential diagnosis for patients presenting with orbital masses of uncertain etiology.

摘要

目的

本报告描述了一例在看似免疫功能正常的宿主中,于一个不太可能的部位——眼眶发现的病例。

观察结果

眼科、神经外科、病理学和传染病科之间的协同多学科方法对于挽救视力和生命至关重要。

结论与意义

据作者所知,这是医学文献中描述的首例原发性眼眶隐球菌病病例。该病例提醒人们注意,隐球菌确实有可能侵入眼眶,对于病因不明的眼眶肿块患者,应将其纳入鉴别诊断范围。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/94b562e42467/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/564cf56d4d3d/gr1a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/0777c6140382/gr1b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/dd4293e2b0fb/gr2a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/489d11ca48dd/gr2b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/fcca1585106f/gr2c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/94b562e42467/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/564cf56d4d3d/gr1a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/0777c6140382/gr1b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/dd4293e2b0fb/gr2a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/489d11ca48dd/gr2b.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/fcca1585106f/gr2c.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38a8/9958422/94b562e42467/gr3.jpg

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1
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本文引用的文献

1
Primary Cutaneous Cryptococcosis due to in an Immunocompetent Host Treated with Itraconazole and Drainage: Case Report and Review of the Literature.免疫功能正常宿主因新型隐球菌感染引发原发性皮肤隐球菌病,采用伊曲康唑及引流治疗:病例报告与文献综述
Case Rep Dermatol. 2021 Feb 4;13(1):89-97. doi: 10.1159/000512289. eCollection 2021 Jan-Apr.
2
Microbe Profile: species complex.微生物简介:种复合体。
Microbiology (Reading). 2020 Sep;166(9):797-799. doi: 10.1099/mic.0.000973.
3
Innate Immune Responses to .对……的固有免疫反应
J Fungi (Basel). 2017 Sep;3(3). doi: 10.3390/jof3030035. Epub 2017 Jul 2.
4
Invasive fungal sinusitis: treatment of the orbit.侵袭性真菌性鼻窦炎:眼眶的治疗
Curr Opin Ophthalmol. 2017 Sep;28(5):522-533. doi: 10.1097/ICU.0000000000000394.
5
Isolated Orbital Aspergillosis in Immunocompetent Patients: A Multicenter Study.免疫功能正常患者的孤立性眼眶曲霉病:一项多中心研究。
Am J Ophthalmol. 2016 May;165:125-32. doi: 10.1016/j.ajo.2016.03.007. Epub 2016 Mar 10.
6
Direct Invasion of the Optic Nerves, Chiasm, and Tracts by Cryptococcus neoformans in an Immunocompetent Host.免疫功能正常宿主中新型隐球菌对视神经、视交叉和视束的直接侵犯
Neurohospitalist. 2015 Oct;5(4):217-22. doi: 10.1177/1941874415569072.
7
Invasive fungal disease of the sinus and orbit: a comparison between mucormycosis and Aspergillus.鼻窦和眼眶的侵袭性真菌病:毛霉病与曲霉病的比较
Br J Ophthalmol. 2016 Feb;100(2):184-8. doi: 10.1136/bjophthalmol-2015-306945. Epub 2015 Jun 25.
8
A Case of Orbital Histoplasmosis.一例眼眶组织胞浆菌病
Ophthalmic Plast Reconstr Surg. 2016 May-Jun;32(3):e71-2. doi: 10.1097/IOP.0000000000000249.
9
Cryptococcus neoformans: historical curiosity to modern pathogen.新型隐球菌:从历史奇闻到现代病原体
Yeast. 2014 Feb;31(2):47-60. doi: 10.1002/yea.2997. Epub 2014 Jan 19.
10
Survival outcomes in acute invasive fungal sinusitis: a systematic review and quantitative synthesis of published evidence.急性侵袭性真菌性鼻窦炎的生存结局:已发表证据的系统评价和定量综合。
Laryngoscope. 2013 May;123(5):1112-8. doi: 10.1002/lary.23912. Epub 2013 Jan 8.