Mayakrishnan Vijayakumar, Thirupathi Anand, Ramamoorthy Kavitha, Annadurai Kaliappan, Prakasam Radha, Gu Yaodong, Kim Choon Young, Ramasamy Mahadevi, Karimpanchola Habeebmon, Kannappan Priya, Vijayakumar Natesan, Venkatesan Kumari Bhuvaneshwari, Singaravelu Anand
Research Academy of Medicine Combining Sports, Ningbo No 2 Hospital, Ningbo 315010, China.
Faculty of Sports Science, Ningbo University, Ningbo 315211, China.
Antioxidants (Basel). 2024 Aug 12;13(8):976. doi: 10.3390/antiox13080976.
A member of the Phyllanthaceae family, is a well-known plant in the tribal areas of Sri Lanka, India's Shaurastra region, Australia, and Malaysia. This study provides information about , a plant with a wide range of therapeutic uses in India. Different extracts from the leaves and roots of were evaluated for their physical and chemical properties, preliminary phytochemical parameters, and pharmacological activities in the current study, followed by their fourier transform infrared spectroscopy (FTIR), gas chromatography-mass spectrometry (GC-MS), antioxidant, and anti-inflammatory properties. The aqueous extract of leaves and roots have more different phytochemical elements than other solvent extracts, according to physico-chemical tests and phytochemical screening. As a result, the FT-IR, GC-MS, antioxidant, and anti-inflammatory activities of an aqueous extract were tested. Studies on hind paw edemas caused by carrageenan in albino rats examined the mean increase in paw volume and the percentage inhibition in paw volume at various time points following the injection of carrageenan (1% /). In comparison to the norm, these inhibitions were statistically significant ( < 0.001). The aqueous extract of leaves and roots have both antioxidative and anti-inflammatory activities, indicating that it has the potential to be used in the formulation of antioxidant and anti-inflammatory medications in the future.
叶下珠科的一种植物，在斯里兰卡的部落地区、印度的索拉什特拉地区、澳大利亚和马来西亚是一种知名植物。本研究提供了关于在印度有广泛治疗用途的一种植物的信息。在本研究中，对该植物叶和根的不同提取物进行了物理和化学性质、初步植物化学参数及药理活性评估，随后检测了它们的傅里叶变换红外光谱（FTIR）、气相色谱 - 质谱联用（GC - MS）、抗氧化和抗炎特性。根据物理化学测试和植物化学筛选，该植物叶和根的水提取物比其他溶剂提取物含有更多不同的植物化学成分。因此，对水提取物进行了FT - IR、GC - MS、抗氧化和抗炎活性测试。在白化大鼠中对角叉菜胶引起的后爪水肿进行的研究，检测了注射角叉菜胶（1% /）后不同时间点爪体积的平均增加量和爪体积的抑制百分比。与正常情况相比，这些抑制作用具有统计学显著性（< 0.001）。该植物叶和根的水提取物具有抗氧化和抗炎活性，表明其未来有潜力用于抗氧化和抗炎药物的制剂中。
