Luo Jian-Yi, Hua Hui-Liang, Chen Zi-Sheng, Zhou Zhao-Zhao, Yang Yan-Fang, Zhou Ping-Xin, He Yu-Tao, Liu Xue-Yuan, Liang Yong-Min
State Key Laboratory of Applied Organic Chemistry, Lanzhou University, and State Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Science, Lanzhou 730000, P.R. China.
Chem Commun (Camb). 2014 Feb 14;50(13):1564-6. doi: 10.1039/c3cc48339h.
A new and efficient metal-free cascade cyclization of 1,6-enynes with aldehydes is developed for the synthesis of tricyclic fluorene derivatives. The reaction involves a radical process and one C(sp(2))-C(sp(2)) and two C(sp(2))-C(sp(3)) bonds are formed simultaneously in one pot by using PivOH and TBHP.
开发了一种新型高效的1,6-烯炔与醛的无金属串联环化反应，用于合成三环芴衍生物。该反应涉及自由基过程，通过使用特戊酸（PivOH）和叔丁基过氧化氢（TBHP），在一锅反应中同时形成一个C(sp(2))-C(sp(2))键和两个C(sp(2))-C(sp(3))键。
