Côté-Daigneault J, Carrier F M, Toledano K, Wartelle-Bladu C, Willems B
Hepatology Service, Department of Medicine, Saint-Luc Hospital, CHUM, University of Montreal, Montreal, Quebec, Canada.
Transpl Infect Dis. 2014 Feb;16(1):130-4. doi: 10.1111/tid.12178. Epub 2014 Jan 3.
Herpes simplex virus (HSV) hepatitis is an uncommon cause of liver failure, but may have a dramatic outcome. We herein present a case report of a liver graft infection by HSV-1 associated with liver failure and encephalitis. A complete hospital chart review of the case and a literature search were undertaken. Literature review suggests that herpes simplex acute liver failure is rare and associated with a poor prognosis, even with early treatment. Novel diagnostic and preventive approaches need to be instituted.
单纯疱疹病毒（HSV）肝炎是肝衰竭的一种罕见病因，但可能产生严重后果。我们在此报告一例1型单纯疱疹病毒（HSV-1）所致肝移植感染病例，该病例伴有肝衰竭和脑炎。我们对该病例进行了完整的医院病历回顾并进行了文献检索。文献回顾表明，单纯疱疹病毒所致急性肝衰竭很罕见，且即便早期治疗，预后也较差。需要采取新的诊断和预防方法。
