Kuptarnond Chusak, Prathanee Sompop
Department of Surgery, Faculty of Medicine, Khon Kaen University, Thailand.
J Med Assoc Thai. 2013 Sep;96 Suppl 4:S142-8.
Controversy still exists concerning the optimum management of aspergilloma.
To evaluate clinical data of patients, the indications for surgery, postoperative complications and results of all treatments of pulmonary aspergillosis compare with data from review literature, to find out the optimum management.
The authors retrospectively reviewed medical records of 45 patients at Srinagarind Hospital who had pulmonary aspergilloma between 1993 and 2008. General data, associated diseases, symptoms, organs involvement, treatments, surgical indications, procedures and complications, and outcome were collected for analysis.
Associated diseases were found in 33 patients (73.3%). Tuberculosis was the most common underlying causes. Hemoptysis, the most frequent symptom, occurred in 29 patients (64.4%0). If 40 patients, they only had lung lesion although 5 patients had multiple organ-involvement. Surgery was performed in 24 patients (53.3%). Hemoptysis was the most common indication and lobectomy was the most frequent procedure. Postoperative complications occurred in 5 cases (20.80%) and mortality rate after surgery = 4.2%. Embolization was done on 4 patients; none of them re-bled. Clinical outcome improved in 36 cases (80%), did not improved in 6 patients (13.3%), and resulted in 3 patients' death (6. 7%).
The most common indication for surgery was hemoptysis. Recurrence of hemoptysis was found in all patients who received selective bronchial artery embolization. Surgical resection is the treatment of choice with acceptable postoperative complications and mortality rate.
关于曲菌球的最佳治疗方法仍存在争议。
评估患者的临床资料、手术适应症、术后并发症以及所有肺曲霉病治疗的结果,并与文献综述中的数据进行比较,以找出最佳治疗方法。
作者回顾性分析了1993年至2008年期间孔敬大学医学院附属诗里拉医院45例肺曲菌球患者的病历。收集一般资料、相关疾病、症状、受累器官、治疗方法、手术适应症、手术步骤及并发症和治疗结果进行分析。
33例患者(73.3%)伴有相关疾病。肺结核是最常见的基础病因。咯血是最常见的症状,29例患者(64.4%)出现咯血。40例患者仅肺部有病变,5例患者有多器官受累。24例患者(53.3%)接受了手术。咯血是最常见的手术适应症,肺叶切除术是最常用的手术方式。术后并发症发生5例(20.8%),手术死亡率为4.2%。4例患者接受了栓塞治疗,均未再出血。36例患者(80%)临床症状改善,6例患者(13.3%)无改善,3例患者死亡(6.7%)。
手术最常见的适应症是咯血。所有接受选择性支气管动脉栓塞治疗的患者均出现咯血复发。手术切除是首选的治疗方法,术后并发症和死亡率均可接受。