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肺曲霉菌瘤咯血控制中的填塞术:高风险患者中可遗忘手术的安全性和有效性。

Plombage for Hemoptysis Control in Pulmonary Aspergilloma: Safety and Effectiveness of Forgettable Surgery in High-Risk Patients.

机构信息

Department of Cardiothoracic Surgery, Military Hospital, Vietnam Military Medical University, Ha Noi, Vietnam.

Department of Thoracic Surgery, Pham Ngoc Thach Hospital, Ho Chi Minh, Vietnam.

出版信息

Ann Thorac Cardiovasc Surg. 2021 Feb 20;27(1):10-17. doi: 10.5761/atcs.oa.20-00169. Epub 2021 Jan 6.

Abstract

OBJECTIVES

To evaluate plombage surgery for hemoptysis control in pulmonary aspergilloma in high-risk patients.

METHODS

This study was carried out on 75 pulmonary aspergilloma patients presenting with hemoptysis that underwent a plombage surgery for approximately 7 years (November 2011-September 2018) at Pham Ngoc Thach Hospital. They revisited the hospital 6 months after plombage surgery and considered plombage removal. The group whose plombage was removed was compared with that whose plombage was retained 6 and 24 months after surgery.

RESULTS

Hemoptysis reduced significantly after surgery. Hemoptysis ceased in 91.67% of the patients and diminished in 8.33% of the patients 6 months after surgery. Similarly, hemoptysis ceased in 87.32% of the patients and diminished in 12.68% of the patients 24 months after surgery. Body mass index (BMI) index, Karnofsky score, and forced expiratory volume in one second (FEV1) increased. Plombage surgery was performed with operative time of 129.5 ± 36.6 min, blood loss during operation of 250.7 ± 163.1 mL, and the number of table tennis balls of 4.22 ± 2.02. No deaths related to plombage surgery were recorded. Plombage was removed in 29 cases because of patients' requirements (89.8%), infection (6.8%), and pain (3.4%). There were no patient developing complications after the treatment and there were no statistically significant differences between the two groups.

CONCLUSIONS

Plombage surgery is safe and effective for hemoptysis control in pulmonary aspergilloma. To minimize the risk of long-term complications, surgeons should remove the plombage 6 months after the initial operation.

摘要

目的

评估在高危患者中,针对肺曲霉菌病咯血控制进行的填塞手术。

方法

本研究纳入了 75 例因咯血而接受了约 7 年(2011 年 11 月至 2018 年 9 月)填塞手术的肺曲霉菌病咯血患者。在填塞术后 6 个月时,他们返回医院并考虑取出填塞物。将取出填塞物的组与手术后 6 个月和 24 个月时保留填塞物的组进行比较。

结果

手术后咯血明显减少。术后 6 个月时,91.67%的患者咯血停止,8.33%的患者咯血减少。同样,术后 24 个月时,87.32%的患者咯血停止,12.68%的患者咯血减少。体重指数(BMI)、卡诺夫斯基评分和一秒用力呼气容积(FEV1)增加。填塞手术的手术时间为 129.5±36.6 分钟,术中失血量为 250.7±163.1 毫升,使用的乒乓球数量为 4.22±2.02 个。没有与填塞手术相关的死亡病例。因患者要求(89.8%)、感染(6.8%)和疼痛(3.4%),共 29 例患者取出了填塞物。治疗后,没有患者出现并发症,两组间无统计学差异。

结论

填塞手术治疗肺曲霉菌病咯血安全有效。为了尽量减少长期并发症的风险,外科医生应在初次手术后 6 个月取出填塞物。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/209e/8043030/78bfe4d907a1/atcs-27-010-g001.jpg

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