固定体积的微滴的阻塞-破裂生成。
Block-and-break generation of microdroplets with fixed volume.
机构信息
School of Engineering and Applied Sciences/Department of Physics, Harvard University, Cambridge, Massachusetts 02138, USA ; Department of Chemical Engineering, Delft University of Technology, Julianalaan 136, 2628 BL Delft, The Netherlands.
Institute of Physical Chemistry, Polish Academy of Sciences, Kasprzaka 44/52, 01-224 Warsaw, Poland ; Institute of Fundamental Technological Research, PAS, Pawinskiego 5B, 02-106 Warsaw, Poland.
出版信息
Biomicrofluidics. 2013 Apr 10;7(2):24108. doi: 10.1063/1.4801637. eCollection 2013.
We introduce a novel type of droplet generator that produces droplets of a volume set by the geometry of the droplet generator and not by the flow rates of the liquids. The generator consists of a classic T-junction with a bypass channel. This bypass directs the continuous fluid around the forming droplets, so that they can fill the space between the inlet of the dispersed phase and the exit of the bypass without breaking. Once filled, the dispersed phase blocks the exit of the bypass and is squeezed by the continuous fluid and broken off from the junction. We demonstrate the fixed-volume droplet generator for (i) the formation of monodisperse droplets from a source of varying flow rates, (ii) the formation of monodisperse droplets containing a gradation of solute concentration, and (iii) the parallel production of monodisperse droplets.
我们介绍了一种新型的液滴发生器，它产生的液滴体积由液滴发生器的几何形状决定，而不是由液体的流速决定。该发生器由一个带有旁路通道的经典 T 型接头组成。该旁路将连续流体引导到形成的液滴周围，从而使它们可以在不破裂的情况下填充分散相入口和旁路出口之间的空间。一旦充满，分散相就会阻塞旁路出口，并被连续流体挤压，从连接处断开。我们展示了固定体积的液滴发生器，用于 (i) 从流量变化的源形成单分散液滴，(ii) 形成具有溶质浓度渐变的单分散液滴，以及 (iii) 并行生产单分散液滴。
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