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本文引用的文献

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Pentapeptide based organogels: the role of adjacently located phenylalanine residues in gel formation.基于五肽的有机凝胶:相邻苯丙氨酸残基在凝胶形成中的作用。
Soft Matter. 2008 Jun 20;4(7):1430-1437. doi: 10.1039/b802205b.
2
Enzyme-controllable delivery of nitric oxide from a molecular hydrogel.分子水凝胶中一氧化氮的酶控制释放。
Chem Commun (Camb). 2013 Oct 14;49(80):9173-5. doi: 10.1039/c3cc45666h. Epub 2013 Aug 29.
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Ultrasound accelerated gelation of novel L-lysine based hydrogelators.超声加速新型 L-赖氨酸基水凝胶形成。
Chem Commun (Camb). 2013 Sep 21;49(73):8045-7. doi: 10.1039/c3cc44767g. Epub 2013 Aug 1.
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Interactions between cellular proteins and morphologically different nanoscale aggregates of small molecules.细胞蛋白质与形态各异的小分子纳米聚集体之间的相互作用。
RSC Adv. 2013 Jun 7;3(21):7704-7707. doi: 10.1039/C3RA41523F.
5
Dephosphorylation of D-peptide derivatives to form biofunctional, supramolecular nanofibers/hydrogels and their potential applications for intracellular imaging and intratumoral chemotherapy.D-肽衍生物的去磷酸化作用以形成具有生物功能的超分子纳米纤维/水凝胶及其在细胞内成像和肿瘤内化疗中的潜在应用。
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Supramolecular filaments containing a fixed 41% paclitaxel loading.含固定 41%紫杉醇载药量的超分子纤维。
Chem Commun (Camb). 2013 May 28;49(43):4968-70. doi: 10.1039/c3cc41896k.
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The importance of the self-assembly process to control mechanical properties of low molecular weight hydrogels.自组装过程对控制低分子量水凝胶力学性能的重要性。
Chem Soc Rev. 2013 Jun 21;42(12):5143-56. doi: 10.1039/c3cs60030k.
8
Novel pH responsive calix[8]arene hydrogelators: self-organization processes at a nanometric scale.新型 pH 响应性杯[8]芳烃水凝胶因子:纳米尺度的自组装过程。
Chem Commun (Camb). 2013 Mar 28;49(25):2530-2. doi: 10.1039/c3cc40374b.
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Perspectives in chemistry--steps towards complex matter.化学新视角——走向复杂物质。
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10
Supramolecular nanostructures formed by anticancer drug assembly.由抗癌药物组装形成的超分子纳米结构。
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含萘氨基酸使碱基-糖-氨基酸缀合物水凝胶化。

A naphthalene-containing amino acid enables hydrogelation of a conjugate of nucleobase-saccharide-amino acids.

机构信息

Department of Chemistry, Brandeis University, 415 South St., Waltham, MA 02454, USA.

出版信息

Chem Commun (Camb). 2014 Feb 25;50(16):1992-4. doi: 10.1039/c3cc48946a.

DOI:10.1039/c3cc48946a
PMID:24412974
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3974899/
Abstract

Here we report the first example of a hydrogelator made of a conjugate of nucleobase-saccharide-amino acids by incorporating L-3-(2-naphthyl)-alanine to the conjugate, which illustrates a facile and effective method for generating bioactive and functional hydrogelators from the basic biological building blocks.

摘要

在这里,我们报告了首例由碱基-糖-氨基酸缀合物通过将 L-3-(2-萘基)-丙氨酸引入缀合物而制成的水凝胶因子的例子,这说明了一种从基本生物构建块生成生物活性和功能性水凝胶因子的简便有效方法。