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Mouse H-2k-restricted cytotoxic T cells recognize antigenic determinants in both the HA1 and HA2 subunits of the influenza A/PR/8/34 hemagglutinin.小鼠H-2k限制性细胞毒性T细胞可识别甲型流感病毒A/PR/8/34血凝素HA1和HA2亚基中的抗原决定簇。
J Exp Med. 1987 Sep 1;166(3):693-701. doi: 10.1084/jem.166.3.693.
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Characterization of two distinct major histocompatibility complex class I Kk-restricted T-cell epitopes within the influenza A/PR/8/34 virus hemagglutinin.甲型流感病毒A/PR/8/34血凝素中两个不同的主要组织相容性复合体I类Kk限制性T细胞表位的特征分析
J Virol. 1991 Oct;65(10):5401-9. doi: 10.1128/JVI.65.10.5401-5409.1991.
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On the role of the transmembrane anchor sequence of influenza hemagglutinin in target cell recognition by class I MHC-restricted, hemagglutinin-specific cytolytic T lymphocytes.关于甲型流感病毒血凝素跨膜锚定序列在I类主要组织相容性复合体限制的、血凝素特异性细胞毒性T淋巴细胞识别靶细胞中的作用。
J Exp Med. 1987 Sep 1;166(3):678-92. doi: 10.1084/jem.166.3.678.
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Cytolytic T lymphocyte and antibody responses to synthetic peptides of influenza virus hemagglutinin.细胞溶解性T淋巴细胞及对流感病毒血凝素合成肽的抗体反应。
J Immunol. 1984 Oct;133(4):2194-201.
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Influenza A virus-specific H-2d restricted cross-reactive cytotoxic T lymphocyte epitope(s) detected in the hemagglutinin HA2 subunit of A/Udorn/72.在A/Udorn/72的血凝素HA2亚基中检测到甲型流感病毒特异性的H-2d限制性交叉反应性细胞毒性T淋巴细胞表位。
Virology. 1995 Dec 20;214(2):445-52. doi: 10.1006/viro.1995.0055.
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Diversity of the class II (I-Ak/I-Ek)-restricted T cell repertoire for influenza hemagglutinin and antigenic drift. Six nonoverlapping epitopes on the HA1 subunit are defined by synthetic peptides.II类（I-Ak/I-Ek）限制性T细胞库对流感血凝素的多样性及抗原漂移。HA1亚基上的六个非重叠表位由合成肽段确定。
J Exp Med. 1989 Aug 1;170(2):383-97. doi: 10.1084/jem.170.2.383.
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A region of the influenza A/NT/60/68 PB2 protein containing an antigenic determinant recognized by murine H-2Dd restricted cytotoxic T lymphocytes.甲型流感病毒/NT/60/68 PB2蛋白的一个区域，该区域含有一个可被小鼠H-2Dd限制性细胞毒性T淋巴细胞识别的抗原决定簇。
Virology. 1988 Nov;167(1):261-8. doi: 10.1016/0042-6822(88)90076-1.
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Cytotoxic T lymphocytes recognize a cross-reactive epitope on the transmembrane region of influenza H1 and H2 hemagglutinins.细胞毒性T淋巴细胞识别甲型流感病毒H1和H2血凝素跨膜区域上的一个交叉反应表位。
Viral Immunol. 1989 Fall;2(3):163-73. doi: 10.1089/vim.1989.2.163.
引用本文的文献
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Harnessing an RNA-mediated chaperone for the assembly of influenza hemagglutinin in an immunologically relevant conformation.利用 RNA 介导的伴侣蛋白将流感血凝素组装成具有免疫相关性的构象。
FASEB J. 2018 May;32(5):2658-2675. doi: 10.1096/fj.201700747RR. Epub 2018 Jan 2.
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CD147 is tightly associated with lactate transporters MCT1 and MCT4 and facilitates their cell surface expression.CD147与乳酸转运蛋白MCT1和MCT4紧密相关，并促进它们在细胞表面的表达。
EMBO J. 2000 Aug 1;19(15):3896-904. doi: 10.1093/emboj/19.15.3896.
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Presentation of a cytosolic antigen by major histocompatibility complex class II molecules requires a long-lived form of the antigen.主要组织相容性复合体II类分子呈递胞质抗原需要抗原的长寿命形式。
Proc Natl Acad Sci U S A. 1996 Dec 10;93(25):14692-7. doi: 10.1073/pnas.93.25.14692.
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A rat CD4 mutant containing the gp120-binding site mediates human immunodeficiency virus type 1 infection.含有gp120结合位点的大鼠CD4突变体介导1型人类免疫缺陷病毒感染。
J Exp Med. 1993 Apr 1;177(4):949-54. doi: 10.1084/jem.177.4.949.
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MHC ligands and peptide motifs: first listing.主要组织相容性复合体（MHC）配体与肽基序：首次列表。
Immunogenetics. 1995;41(4):178-228. doi: 10.1007/BF00172063.
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Processing of major histocompatibility class I-restricted antigens in the endoplasmic reticulum.内质网中主要组织相容性复合体I类限制抗原的加工
J Exp Med. 1995 Apr 1;181(4):1481-91. doi: 10.1084/jem.181.4.1481.
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T cell recognition of an HLA-A2-restricted epitope derived from a cleaved signal sequence.T细胞对源自裂解信号序列的HLA - A2限制性表位的识别。
J Exp Med. 1994 Nov 1;180(5):1989-94. doi: 10.1084/jem.180.5.1989.
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The role of beta-hydroxyaspartate and adjacent carboxylate residues in the first EGF domain of human factor IX.β-羟基天冬氨酸和相邻羧基残基在人凝血因子IX首个表皮生长因子结构域中的作用。
EMBO J. 1988 Jul;7(7):2053-61. doi: 10.1002/j.1460-2075.1988.tb03045.x.
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Characterization of two distinct major histocompatibility complex class I Kk-restricted T-cell epitopes within the influenza A/PR/8/34 virus hemagglutinin.甲型流感病毒A/PR/8/34血凝素中两个不同的主要组织相容性复合体I类Kk限制性T细胞表位的特征分析
J Virol. 1991 Oct;65(10):5401-9. doi: 10.1128/JVI.65.10.5401-5409.1991.
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Overlapping cytotoxic T-lymphocyte and B-cell antigenic sites on the influenza virus H5 hemagglutinin.流感病毒H5血凝素上重叠的细胞毒性T淋巴细胞和B细胞抗原位点。
J Virol. 1990 Dec;64(12):6246-51. doi: 10.1128/JVI.64.12.6246-6251.1990.
本文引用的文献
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Stimulation of anti-influenza cytolytic T lymphocytes by CNBr cleavage fragments of the viral hemagglutinin.病毒血凝素的溴化氰裂解片段对抗流感细胞溶解T淋巴细胞的刺激作用。
J Immunol. 1981 Sep;127(3):1122-5.
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Decrease in macrophage antigen catabolism caused by ammonia and chloroquine is associated with inhibition of antigen presentation to T cells.氨和氯喹引起的巨噬细胞抗原分解代谢减少与抗原呈递给T细胞的抑制相关。
Proc Natl Acad Sci U S A. 1982 Jan;79(1):175-8. doi: 10.1073/pnas.79.1.175.
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Oligonucleotide-directed mutagenesis using M13-derived vectors: an efficient and general procedure for the production of point mutations in any fragment of DNA.使用M13衍生载体的寡核苷酸定向诱变：在任何DNA片段中产生点突变的高效通用方法。
Nucleic Acids Res. 1982 Oct 25;10(20):6487-500. doi: 10.1093/nar/10.20.6487.
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Cytotoxic T-cell immunity to influenza.针对流感的细胞毒性T细胞免疫
N Engl J Med. 1983 Jul 7;309(1):13-7. doi: 10.1056/NEJM198307073090103.
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Immunogenic properties of the small chain HA2 of the haemagglutinin of influenza viruses.流感病毒血凝素小链HA2的免疫原性特性
J Gen Virol. 1984 Jan;65 ( Pt 1):173-83. doi: 10.1099/0022-1317-65-1-173.
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Recombinant vaccinia virus primes and stimulates influenza haemagglutinin-specific cytotoxic T cells.重组痘苗病毒引发并刺激流感血凝素特异性细胞毒性T细胞。
Nature. 1984;311(5986):578-9. doi: 10.1038/311578a0.
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General method for production and selection of infectious vaccinia virus recombinants expressing foreign genes.表达外源基因的感染性痘苗病毒重组体的生产和选择通用方法。
J Virol. 1984 Mar;49(3):857-64. doi: 10.1128/JVI.49.3.857-864.1984.
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Complete nucleotide sequence of the haemagglutinin gene from a human influenza virus of the Hong Kong subtype.一株香港亚型人流感病毒血凝素基因的完整核苷酸序列
Nucleic Acids Res. 1980 Jun 25;8(12):2561-75. doi: 10.1093/nar/8.12.2561.
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