Dotta Blake T, Murugan Nirosha J, Karbowski Lukasz M, Lafrenie Robert M, Persinger Michael A
Biomolecular Sciences Program, Laurentian University, 935 Ramsey Lake Road, Sudbury, Ontario, Canada, P3E 2C6.
Naturwissenschaften. 2014 Feb;101(2):87-94. doi: 10.1007/s00114-013-1133-3. Epub 2014 Jan 15.
During the first 24 h after removal from incubation, melanoma cells in culture displayed reliable increases in emissions of photons of specific wavelengths during discrete portions of this interval. Applications of specific filters revealed marked and protracted increases in infrared (950 nm) photons about 7 h after removal followed 3 h later by marked and protracted increases in near ultraviolet (370 nm) photon emissions. Specific wavelengths within the visible (400 to 800 nm) peaked 12 to 24 h later. Specific activators or inhibitors for specific wavelengths based upon Cosic's resonant recognition model elicited either enhancement or diminishment of photons at the specific wavelength as predicted. Inhibitors or activators predicted for other wavelengths, even within 10 nm, were less or not effective. There is now evidence for quantitative coupling between the wavelength of photon emissions and intrinsic cellular chemistry. The results are consistent with initial activation of signaling molecules associated with infrared followed about 3 h later by growth and protein-structural factors associated with ultraviolet. The greater-than-expected photon counts compared with raw measures through the various filters, which also function as reflective material to other photons, suggest that photons of different wavelengths might be self-stimulatory and could play a significant role in cell-to-cell communication.
在从培养环境中取出后的最初24小时内,培养中的黑色素瘤细胞在这段时间的特定阶段,特定波长光子的发射量出现了可靠的增加。使用特定滤光片发现,取出约7小时后,红外(950纳米)光子显著且持续增加,3小时后,近紫外(370纳米)光子发射也显著且持续增加。可见光范围内(400至800纳米)的特定波长在12至24小时后达到峰值。基于科西奇共振识别模型的特定波长的特定激活剂或抑制剂,如预期的那样,引发了特定波长光子的增强或减少。针对其他波长预测的抑制剂或激活剂,即使在10纳米范围内,效果也较差或无效。现在有证据表明光子发射波长与细胞内化学性质之间存在定量耦合。结果与最初与红外相关的信号分子的激活一致,约3小时后,与紫外相关产生生长和蛋白质结构因子。与通过各种滤光片的原始测量相比,光子计数高于预期,这些滤光片对其他光子也起到反射材料的作用,这表明不同波长的光子可能具有自我刺激作用,并且可能在细胞间通讯中发挥重要作用。