State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming 650201, Yunnan, PR China.
Org Lett. 2014 Jan 17;16(2):528-31. doi: 10.1021/ol403408m. Epub 2013 Dec 26.
One Myrioneuron alkaloid, myrifabine (1), the first example of a dimer with 12 chiral centers embraced in a decacyclic novel skeleton, was isolated from Myrioneuron faberi . Its structure was elucidated by spectroscopic data and single-crystal X-ray diffraction. The antimicrobial and cytotoxic activities of 1 were evaluated in vitro.
从 Faberi 美登木中分离得到一个美登木烷型倍半萜生物碱美福因(1),这是首例包含 12 个手性中心并被一个十氢环新型骨架环抱的二聚体,其结构通过波谱数据和单晶 X 射线衍射解析。测定了化合物 1 的体外抗菌和细胞毒活性。