Weldon David
Scott & White Clinic, College Station, Texas, USA.
Allergy Asthma Proc. 2014 Jan-Feb;35(1):4-9. doi: 10.2500/aap.2014.35.3713.
Patients with urticaria and/or angioedema have several reasons to have a poor quality of life (QoL). The intensity of pruritus and density of involvement compromise a patient's lifestyle as well as aggravate stressors that affect physical and psychiatric conditions. The burden of illness is significant in not only costs for emergent practitioner visits, but, often, unnecessary laboratory testing and medication expenses. Questionnaires that assess a patient's QoL serve to document benefit to therapies. Objectively documenting changes that are important to patients with urticaria and/or angioedema allows the patients and clinician to accurately assess effectiveness of therapies over long periods of time. Specific surveys that address urticaria (CU-Q2oL and UAS) and angioedema (AE-QoL questionnaire) allow simplified and sensitive assessments for patients with the corresponding condition. Common components of appropriate surveys assess not only intensity of pruritus and wheals but also impact on sleep, interpersonal relationships, and appearances. In considering the most important aspects of several surveys, an example of a survey is provided that focuses on the patient's perception of how their urticaria and/or angioedema impacts their QoL.
患有荨麻疹和/或血管性水肿的患者有多种导致生活质量低下的原因。瘙痒的强度和受累程度会影响患者的生活方式，并加剧那些影响身体和精神状况的应激源。疾病负担不仅体现在急诊就诊的费用上，还常常体现在不必要的实验室检查和药物费用上。评估患者生活质量的问卷有助于记录治疗效果。客观记录对荨麻疹和/或血管性水肿患者重要的变化，能使患者和临床医生长期准确评估治疗效果。针对荨麻疹（慢性荨麻疹生活质量问卷和荨麻疹活动度评分）和血管性水肿（血管性水肿生活质量问卷）的特定调查，能为相应病症的患者提供简化且敏感的评估。合适调查的共同组成部分不仅评估瘙痒和风团的强度，还评估对睡眠、人际关系和外貌的影响。在考虑多项调查的最重要方面时，给出了一个以患者对其荨麻疹和/或血管性水肿如何影响其生活质量的认知为重点的调查示例。
