产甾醇分枝杆菌新金色亚种菌株VKM Ac-1815D的全基因组序列
Complete Genome Sequence of Sterol-Transforming Mycobacterium neoaurum Strain VKM Ac-1815D.
作者信息
Shtratnikova Victoriya Y, Bragin Eugeny Y, Dovbnya Dmitry V, Pekov Yury A, Schelkunov Mikhail I, Strizhov Nicolai, Ivashina Tanya V, Ashapkin Vasily V, Donova Marina V
机构信息
Center of Innovations and Technologies Biologically Active Compounds and Their Applications, Moscow, Russia.
出版信息
Genome Announc. 2014 Jan 16;2(1):e01177-13. doi: 10.1128/genomeA.01177-13.
Abstract
Mycobacterium neoaurum strain VKM Ac-1815D produces 4-androstene-3,17-dione as a major compound from phytosterols. Here, we report the complete genome sequence of the strain. The genome consists of a single circular 5,438,190-bp chromosome, with a G+C content of 66.88%, containing 5,318 putative open reading frames (ORFs), 46 tRNAs, and 6 rRNAs. Arrays of cholesterol metabolism genes are randomly clustered throughout the chromosome.
摘要
新金色分枝杆菌菌株VKM Ac-1815D以植物甾醇为主要原料生产4-雄烯-3,17-二酮。在此，我们报告该菌株的完整基因组序列。基因组由一条单一的环状5,438,190碱基对染色体组成，G+C含量为66.88%，包含5,318个推定的开放阅读框（ORF）、46个tRNA和6个rRNA。胆固醇代谢基因阵列随机分布于整个染色体。
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