Qureishi Ali, Lee Yan, Belfield Katherine, Birchall John P, Daniel Matija
Otolaryngology Head and Neck Surgery, Northampton General Hospital, Northampton, UK.
NIHR Nottingham Hearing Biomedical Research Unit, Nottingham, UK.
Infect Drug Resist. 2014 Jan 10;7:15-24. doi: 10.2147/IDR.S39637.
Acute otitis media and otitis media with effusion are common childhood disorders, a source of significant morbidity, and a leading cause of antibiotic prescription in primary health care. Although effective treatments are available, some shortcomings remain, and thus better treatments would be welcome. Recent discoveries within the field of otitis media research relating to its etiology and pathogenesis have led to further investigation aimed at developing novel treatments. This article provides a review of the latest evidence relating to the understanding of acute otitis media and otitis media with effusion, current treatment strategies, their limitations, new areas of research, and novel strategies for treatment.
急性中耳炎和分泌性中耳炎是常见的儿童疾病,是导致显著发病的原因,也是初级卫生保健中抗生素处方的主要原因。尽管有有效的治疗方法,但仍存在一些不足之处,因此更有效的治疗方法将受到欢迎。中耳炎研究领域最近在病因学和发病机制方面的发现促使人们进一步开展研究,以开发新的治疗方法。本文综述了有关急性中耳炎和分泌性中耳炎的最新认识、当前的治疗策略、其局限性、新的研究领域以及新的治疗策略的最新证据。