Acharya Anirudh B, Surve Sai M, Thakur Srinath L
MDS, Professor, Department of Periodontics, S.D.M. College of Dental Sciences & Hospital, Karnataka, India.
MDS, Consultant Periodontist, Private Practice, Mumbai-400103, Borivali, Maharashtra, India.
J Clin Exp Dent. 2013 Feb 1;5(1):e18-22. doi: 10.4317/jced.50955.
Dentinal hypersensitivity is a commonly encountered problem with varied treatment options for its management. A large number of home use products have been tested and used for the management of dentinal hypersensitivity. This 8 week clinical trial investigates the temporal efficacy of commercially available calcium sodium phosphosilicate containing toothpaste in comparison to a potassium nitrate containing toothpaste.
A total 20 subjects between the ages of 18 to 65 years were screened for a visual analogue score (VAS) for sensitivity of 5 or more by testing with a cold stimulus and randomly divided into test and positive control groups. Baseline sensitivity VAS scores to air evaporative stimulus were recorded for minimum two teeth. The subjects were prescribed respective dentifrices and revaluated for sensitivity scores at 2, 4 and 8 weeks.
The study demonstrated reduction in symptoms for all treatment groups from baseline to 2, 4 and 8 weeks. The calcium sodium phosphosilicate group showed a higher degree of effectiveness at reducing hypersensitivity to air evaporative stimulus at 2 weeks, than commercially available potassium nitrate. However, there was no significant difference in scores of subjects using the calcium sodium phosphosilicate toothpaste as compared to potassium nitrate at 4 weeks and 8 weeks.
Calcium sodium phosphosilicate showed greater reduction in sensitivity compared to potassium nitrate at an earlier stage which is of high clinical value. However, based on the findings of the present study long term effects of calcium sodium phosphosilicate seem to be less promising than previously claimed. Key words:Dentinal desensitizing agents, dentinal hypersensitivity, toothpaste, pain measurement.
牙本质过敏是一个常见问题，有多种治疗方法。大量家用产品已被测试并用于治疗牙本质过敏。这项为期8周的临床试验研究了市售含磷酸硅钙钠牙膏与含硝酸钾牙膏相比的短期疗效。
通过冷刺激测试，对20名年龄在18至65岁之间、视觉模拟评分（VAS）敏感度为5或更高的受试者进行筛查，并随机分为测试组和阳性对照组。记录至少两颗牙齿对空气蒸发刺激的基线敏感度VAS评分。给受试者开相应的牙膏，并在2周、4周和8周时重新评估敏感度评分。
研究表明，所有治疗组从基线到2周、4周和8周症状均有所减轻。与市售硝酸钾相比，磷酸硅钙钠组在2周时对空气蒸发刺激的过敏敏感度降低程度更高。然而，在4周和8周时，使用磷酸硅钙钠牙膏的受试者与使用硝酸钾牙膏的受试者评分无显著差异。
与硝酸钾相比，磷酸硅钙钠在早期阶段显示出更大的敏感度降低，具有较高的临床价值。然而，根据本研究结果，磷酸硅钙钠的长期效果似乎不如先前声称的那样有前景。关键词：牙本质脱敏剂、牙本质过敏、牙膏、疼痛测量。
