• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

氟化物和含硅酸钠钙的牙膏治疗牙本质过敏症的对比评价。

Comparative evaluation of fluorinol and calcium sodium phosphosilicate-containing toothpastes in the treatment of dentin hypersensitivity.

机构信息

Department of Periodontology, JSS Dental College & Hospital, JSS Academy of Higher Education & Research, Mysuru, India.

出版信息

Int J Dent Hyg. 2021 Nov;19(4):421-428. doi: 10.1111/idh.12495. Epub 2021 Apr 16.

DOI:10.1111/idh.12495
PMID:33756064
Abstract

BACKGROUND

Dentin hypersensitivity is one of the most commonly encountered clinical problems. Various desensitizing agents have been widely used in the management of dentin hypersensitivity. Fluorinol, a fluoride-containing agent, has shown to be effective in fluoridating the hydroxyapatite crystal and thus reduce enamel solubility. Calcium sodium phosphosilicate mechanically occludes open tubules and releases calcium and phosphorous to remineralize tooth structure.

OBJECTIVE

To compare and assess the efficacy of fluorinol-containing toothpaste with 7.5% sodium calcium phosphosilicate-containing toothpaste in reducing dentin hypersensitivity.

METHODOLOGY

Thorough oral prophylaxis was done, and the patients were subjected to the washout phase, after which they were randomly allocated to the two study groups, Group A-fluorinol-containing toothpaste, Group B-sodium calcium phosphosilicate-containing toothpaste. Patients were recalled on 2 , 3 and 4 weeks, and sensitivity was assessed using VAS scores by means of tactile, evaporative and cold water stimuli. Oral health-related quality of life was assessed using OHIP-14 questionnaire at baseline and 4 weeks.

RESULT

Compared to baseline, there was a significant decrease in dentin hypersensitivity in both the groups. The VAS scores for tactile stimuli were significantly lower in group A at 3 and 4 weeks.

CONCLUSION

Fluorinol-containing toothpaste was shown to be effective in reducing dentinal hypersensitivity. Hence, it can be used routinely in the management of dentin hypersensitivity.

摘要

背景

牙本质过敏是最常见的临床问题之一。各种脱敏剂已广泛用于牙本质过敏症的治疗。含氟化物的氟诺隆被证明能有效地氟化羟基磷灰石晶体,从而降低釉质溶解度。硅钙钠磷灰石通过机械阻塞开放的小管并释放钙和磷来使牙体结构再矿化。

目的

比较并评估含氟诺隆的牙膏与含 7.5%硅钙钠磷灰石的牙膏在减轻牙本质过敏方面的疗效。

方法

进行彻底的口腔预防,患者进入冲洗阶段,然后随机分配到两组,A 组-含氟诺隆的牙膏,B 组-含硅钙钠磷灰石的牙膏。患者在第 2、3 和 4 周进行随访,使用 VAS 评分通过触觉、蒸发和冷水刺激来评估敏感性。基线和 4 周时使用 OHIP-14 问卷评估口腔健康相关生活质量。

结果

与基线相比,两组的牙本质过敏症均有显著减轻。在第 3 和第 4 周,A 组的触觉刺激 VAS 评分明显降低。

结论

含氟诺隆的牙膏在减轻牙本质过敏方面有效。因此,它可以常规用于牙本质过敏症的治疗。

相似文献

1
Comparative evaluation of fluorinol and calcium sodium phosphosilicate-containing toothpastes in the treatment of dentin hypersensitivity.氟化物和含硅酸钠钙的牙膏治疗牙本质过敏症的对比评价。
Int J Dent Hyg. 2021 Nov;19(4):421-428. doi: 10.1111/idh.12495. Epub 2021 Apr 16.
2
Exploratory randomised controlled clinical study to evaluate the comparative efficacy of two occluding toothpastes - a 5% calcium sodium phosphosilicate toothpaste and an 8% arginine/calcium carbonate toothpaste - for the longer-term relief of dentine hypersensitivity.探索性随机对照临床试验评估两种封闭牙膏的疗效比较 - 一种 5% 磷酸硅酸钠钙牙膏和一种 8% 精氨酸/碳酸钙牙膏 - 用于长期缓解牙本质过敏。
J Dent. 2017 May;60:36-43. doi: 10.1016/j.jdent.2017.02.009. Epub 2017 Feb 20.
3
Comparing the efficacy in providing instant relief of dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride relative to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride, and to a control toothpaste with 1450 ppm fluoride: a three-day clinical study in New Jersey, USA.将一款含有8.0%精氨酸、碳酸钙和1450 ppm氟化物的新型牙膏,与一款含有2%钾离子和1450 ppm氟化物的基准脱敏牙膏以及一款含有1450 ppm氟化物的对照牙膏相比较,评估它们在即时缓解牙本质过敏方面的疗效:在美国新泽西州进行的一项为期三天的临床研究。
J Clin Dent. 2009;20(4):123-30.
4
Comparison of clinical efficacy of three toothpastes in reducing dentin hypersensitivity.三种牙膏降低牙本质过敏症临床疗效的比较。
J Clin Dent. 2011;22(4):113-20.
5
Comparing the efficacy in providing instant relief of dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a benchmark desensitizing toothpaste containing 2% potassium ion and 1450 ppm fluoride, and to a control toothpaste with 1450 ppm fluoride: a three-day clinical study in Mississauga, Canada.将一款含有8.0%精氨酸、碳酸钙和1450 ppm氟化物的新型牙膏与一款含有2%钾离子和1450 ppm氟化物的基准脱敏牙膏以及一款含有1450 ppm氟化物的对照牙膏在缓解牙本质过敏即时效果方面的功效进行比较:在加拿大密西沙加进行的一项为期三天的临床研究。
J Clin Dent. 2009;20(4):115-22.
6
Comparing the efficacy in reducing dentin hypersensitivity of a new toothpaste containing 8.0% arginine, calcium carbonate, and 1450 ppm fluoride to a benchmark commercial desensitizing toothpaste containing 2% potassium ion: an eight-week clinical study in Rome, Italy.将一款含有8.0%精氨酸、碳酸钙和1450 ppm氟化物的新型牙膏与一款含2%钾离子的基准商用脱敏牙膏在减轻牙本质过敏方面的疗效进行比较:在意大利罗马进行的一项为期八周的临床研究。
J Clin Dent. 2009;20(4):137-43.
7
Comparative evaluation of the efficacy of three commercially available toothpastes on dentin hypersensitivity reduction: an eight-week clinical study.三种市售牙膏减少牙本质过敏症疗效的比较评估:一项为期八周的临床研究。
J Clin Dent. 2011;22(4):121-7.
8
Use of a toothpaste containing 8% arginine and calcium carbonate for immediate and lasting relief of dentin hypersensitivity: A simple and effective in-office procedure.使用含有8%精氨酸和碳酸钙的牙膏实现牙本质过敏的即时和持久缓解:一种简单有效的诊室治疗方法。
Am J Dent. 2018 Jun;31(3):135-140.
9
A randomised controlled trial investigating efficacy of a novel toothpaste containing calcium silicate and sodium phosphate in dentine hypersensitivity pain reduction compared to a fluoride control toothpaste.一项随机对照试验,旨在研究一种含有硅酸钙和磷酸钠的新型牙膏与含氟对照牙膏相比,在减轻牙本质过敏疼痛方面的疗效。
J Dent. 2020 Jul;98:103320. doi: 10.1016/j.jdent.2020.103320. Epub 2020 Jun 1.
10
Comparative efficacy of two treatment regimens combining in-office and at-home programs for dentin hypersensitivity relief: a 24-week clinical study.两种结合诊室治疗和家庭治疗方案缓解牙本质敏感的疗效比较:一项为期24周的临床研究。
Am J Dent. 2012 Jun;25(3):146-52.

引用本文的文献

1
Bioactive glass products for the treatment of dentin hypersensitivity: a scoping review.用于治疗牙本质过敏的生物活性玻璃产品:一项范围综述
Clin Oral Investig. 2025 Sep 17;29(10):464. doi: 10.1007/s00784-025-06516-w.
2
Efficacy of bioactive glass-based desensitizer compared to other desensitizing agents or techniques in dentin hypersensitivity: a systematic review.与其他脱敏剂或技术相比,生物活性玻璃基脱敏剂治疗牙本质过敏症的疗效:一项系统评价
BMC Oral Health. 2025 Jun 3;25(1):899. doi: 10.1186/s12903-025-06288-5.
3
Improving Oral Health with Fluoride-Free Calcium-Phosphate-Based Biomimetic Toothpastes: An Update of the Clinical Evidence.
使用无氟磷酸钙基仿生牙膏改善口腔健康:临床证据更新
Biomimetics (Basel). 2023 Jul 27;8(4):331. doi: 10.3390/biomimetics8040331.
4
Evaluation of Bioactive Glass Treatment for Dentin Hypersensitivity: A Systematic Review.生物活性玻璃治疗牙本质过敏症的评估:一项系统综述
Biomedicines. 2023 Jul 14;11(7):1992. doi: 10.3390/biomedicines11071992.
5
Home Oral Care with Biomimetic Hydroxyapatite vs. Conventional Fluoridated Toothpaste for the Remineralization and Desensitizing of White Spot Lesions: Randomized Clinical Trial.仿生羟磷灰石家用口腔护理与含氟常规牙膏在再矿化和脱敏白色斑点病变中的效果比较:随机临床试验。
Int J Environ Res Public Health. 2022 Jul 16;19(14):8676. doi: 10.3390/ijerph19148676.