DNA 低甲基化剂对体外潜伏感染小鼠神经节中单纯疱疹病毒再激活的影响。简报。
The effect of DNA hypomethylating agents on the reactivation of herpes simplex virus from latently infected mouse ganglia in vitro. Brief report.
作者信息
Whitby A J, Blyth W A, Hill T J
机构信息
Department of Microbiology, University of Bristol, Medical School, U.K.
出版信息
Arch Virol. 1987;97(1-2):137-44. doi: 10.1007/BF01310742.
PMID:2446591
Abstract
Effects of DNA hypomethylating agents on reactivation of herpes simplex virus from latently infected mouse ganglia in vitro were examined. L-ethionine and 5-azacytidine increased the incidence of reactivation. Dimethylsulphoxide and 5-azacytidine allowed earlier detection of virus.
摘要
研究了DNA低甲基化剂对体外潜伏感染小鼠神经节中单纯疱疹病毒再激活的影响。L-乙硫氨酸和5-氮杂胞苷增加了再激活的发生率。二甲基亚砜和5-氮杂胞苷能更早检测到病毒。
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