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非洲女性中的高血压及高血压性心脏病

Hypertension and hypertensive heart disease in African women.

作者信息

Sliwa Karen, Ojji Dike, Bachelier Katrin, Böhm Michael, Damasceno Albertino, Stewart Simon

机构信息

Department of Medicine, Hatter Institute for Cardiovascular Research in Africa and IIDMM, Faculty of Health Sciences, Groote Schuur Hospital and University of Cape Town, Observatory, Cape Town, 7925, South Africa,

出版信息

Clin Res Cardiol. 2014 Jul;103(7):515-23. doi: 10.1007/s00392-014-0660-z. Epub 2014 Jan 28.

Abstract

Hypertension and hypertensive heart disease is one of the main contributors to a growing burden of non-communicable forms of cardiovascular disease around the globe. The recently published global burden of disease series showed a 33 % increase of hypertensive disorders in pregnancy in the past two decades with long-term consequences. Africans, particularly younger African women, appear to be bearing the brunt of this increasing public health problem. Hypertensive heart disease is particularly problematic in pregnancy and is an important contributor to maternal case-fatality. European physicians increasingly need to attend to patients from African decent and need to know about unique aspects of disease presentation and pharmacological as well as non-pharmacological care. Reductions in salt consumption, as well as timely detection and treatment of hypertension and hypertensive heart disease remain a priority for effective primary and secondary prevention of CVD (particularly stroke and CHF) in African women. This article reviews the pattern, potential causes and consequences and treatment of hypertension and hypertensive heart disease in African women, identifying the key challenges for effective primary and secondary prevention in this regard.

摘要

高血压及高血压性心脏病是全球非传染性心血管疾病负担不断加重的主要原因之一。最近发布的全球疾病负担系列报告显示,在过去二十年中,妊娠期高血压疾病增加了33%,且具有长期后果。非洲人,尤其是年轻的非洲女性,似乎首当其冲地承受着这一日益严重的公共卫生问题。高血压性心脏病在妊娠期尤其成问题,是孕产妇死亡的重要原因。欧洲医生越来越需要诊治非洲裔患者,并且需要了解疾病表现、药物治疗以及非药物治疗方面的独特之处。减少盐的摄入量,以及及时发现和治疗高血压及高血压性心脏病,仍然是有效预防非洲女性心血管疾病(尤其是中风和心力衰竭)一级和二级预防的重点。本文综述了非洲女性高血压及高血压性心脏病的模式、潜在原因、后果及治疗方法,确定了这方面有效一级和二级预防的关键挑战。

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