Santos Mônica, Fonseca Hannah Monteiro, Jalkh Alex Panizza, Gomes Gabriela Piraice, Cavalcante Andrea de Souza
Alfredo da Matta Foundation, MD, PhD in Tropical Medicine - Dermatologist at the Alfredo da Matta Foundation (Fundação Alfredo da Matta - FUAM). Professor of dermatology at the State University of Amazonas (Universidade do Estado do Amazonas - UEA) - Manaus (AM), Brazil.
State University of Amazonas, ManausAM, Brazil, Medical student at the State University of Amazonas (Universidade do Estado do Amazonas - UEA) - Manaus (AM), Brazil.
An Bras Dermatol. 2013 Nov-Dec;88(6):913-6. doi: 10.1590/abd1806-4841.20132090.
Psoriasis is a chronic inflammatory disease of multifactorial etiology, with participation of genetic, autoimmune and environmental factors. Recent studies have demonstrated the role of inflammatory cells and mediators in the pathogenesis of psoriasis, which is now defined as a systemic and autoimmune inflammatory disease that may be associated with other diseases of inflammatory nature.
To evaluate the occurrence of obesity and dyslipidemia in patients with psoriasis treated at a dermatology clinic in Manaus.
We performed a prospective descriptive study to assess the prevalence of obesity and dyslipidemia in patients with psoriasis. Besides the recommended dermatological care, a physical examination was performed to measure weight, height and waist circumference.
We included 72 patients, 44 (61.1%) female and 28 (38.9%) male, with a mean age of 51.0 years ± 15.9 years. As for body mass index (BMI), 16 (22.2%) were overweight and 20 (27.8%) were obese. In the analysis of waist circumference in relation to gender, we found that 79.5% of women surveyed had central obesity, a percentage statistically higher than that observed among men (42.9%) at the 5% level of significance (p = 0.001). Regarding the diagnosis of dyslipidemia, 29 (65.9%) females and 22 (78.6%) males showed alterations in lipid profile.
The occurrence of dyslipidemia and obesity in patients with psoriasis can affect life quality and expectancy, increasing the risk of systemic and metabolic diseases, which makes periodic investigation of these comorbidities in patients with psoriasis mandatory.
银屑病是一种病因多因素的慢性炎症性疾病，涉及遗传、自身免疫和环境因素。最近的研究已证实炎症细胞和介质在银屑病发病机制中的作用，银屑病现被定义为一种全身性自身免疫性炎症性疾病，可能与其他炎症性疾病相关。
评估在玛瑙斯一家皮肤科诊所接受治疗的银屑病患者中肥胖和血脂异常的发生率。
我们进行了一项前瞻性描述性研究，以评估银屑病患者中肥胖和血脂异常的患病率。除了推荐的皮肤科护理外，还进行了体格检查以测量体重、身高和腰围。
我们纳入了72例患者，其中44例（61.1%）为女性，28例（38.9%）为男性，平均年龄为51.0岁±15.9岁。至于体重指数（BMI），16例（22.2%）超重，20例（27.8%）肥胖。在按性别分析腰围时，我们发现接受调查的女性中有79.5%存在中心性肥胖，这一百分比在5%的显著性水平上统计学上高于男性（42.9%）（p = 0.001）。关于血脂异常的诊断，29例（65.9%）女性和22例（78.6%）男性的血脂谱出现异常。
银屑病患者中血脂异常和肥胖的发生会影响生活质量和预期寿命，增加全身性和代谢性疾病的风险，这使得对银屑病患者定期调查这些合并症成为必要。
