Sofi Francesco, Macchi Claudio, Abbate Rosanna, Gensini Gian Franco, Casini Alessandro
1Department of Clinical and Experimental Medicine,University of Florence,Largo Brambilla 3,50134 Florence,Italy.
3Don Carlo Gnocchi Foundation Italy,IRCCS,Florence,Italy.
Public Health Nutr. 2014 Dec;17(12):2769-82. doi: 10.1017/S1368980013003169. Epub 2013 Nov 29.
To update previous meta-analyses of cohort studies that investigated the association between the Mediterranean diet and health status and to utilize data coming from all of the cohort studies for proposing a literature-based adherence score to the Mediterranean diet.
We conducted a comprehensive literature search through all electronic databases up to June 2013.
Cohort prospective studies investigating adherence to the Mediterranean diet and health outcomes. Cut-off values of food groups used to compute the adherence score were obtained.
The updated search was performed in an overall population of 4 172 412 subjects, with eighteen recent studies that were not present in the previous meta-analyses.
A 2-point increase in adherence score to the Mediterranean diet was reported to determine an 8 % reduction of overall mortality (relative risk = 0·92; 95 % CI 0·91, 0·93), a 10 % reduced risk of CVD (relative risk = 0·90; 95 % CI 0·87, 0·92) and a 4 % reduction of neoplastic disease (relative risk = 0·96; 95 % CI 0·95, 0·97). We utilized data coming from all cohort studies available in the literature for proposing a literature-based adherence score. Such a score ranges from 0 (minimal adherence) to 18 (maximal adherence) points and includes three different categories of consumption for each food group composing the Mediterranean diet.
The Mediterranean diet was found to be a healthy dietary pattern in terms of morbidity and mortality. By using data from the cohort studies we proposed a literature-based adherence score that can represent an easy tool for the estimation of adherence to the Mediterranean diet also at the individual level.
更新既往关于队列研究的荟萃分析，该分析探讨了地中海饮食与健康状况之间的关联，并利用所有队列研究的数据，提出基于文献的地中海饮食依从性评分。
我们通过检索截至2013年6月的所有电子数据库进行了全面的文献检索。
队列前瞻性研究，调查地中海饮食的依从性和健康结局。获取用于计算依从性评分的食物组的临界值。
在总共4172412名受试者中进行了更新检索，其中有18项近期研究未纳入既往的荟萃分析。
据报告，地中海饮食依从性评分增加2分可使总死亡率降低8%（相对风险=0.92；95%可信区间0.91，0.93），心血管疾病风险降低10%（相对风险=0.90；95%可信区间0.87，0.92），肿瘤性疾病风险降低4%（相对风险=0.96；95%可信区间0.95，0.97）。我们利用文献中所有可用队列研究的数据，提出基于文献的依从性评分。该评分范围从0（最低依从性）到18分（最高依从性），并针对构成地中海饮食的每个食物组包括三种不同的消费类别。
就发病率和死亡率而言，地中海饮食被发现是一种健康的饮食模式。通过使用队列研究的数据，我们提出了一种基于文献的依从性评分，该评分也可作为在个体水平上评估地中海饮食依从性的简便工具。
