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巴西巴拉那州州府城镇献血者的血液废弃率以及传染病和感染性疾病的流行情况。

Blood discard rate and the prevalence of infectious and contagious diseases in blood donors from provincial towns of the state of Paraná, Brazil.

作者信息

Borelli Sueli Donizete, Mazzola Jocimara Costa, Matta Alessandra Cristina Gobbi, Takemoto Angélica Yukari, Bértoli Marta

机构信息

Universidade Estadual de Maringá - UEM, Maringá, PR, Brazil.

Universidade Estadual de Maringá - UEM, Maringá, PR, Brazil ; Faculdade Ingá, Maringá, PR, Brazil.

出版信息

Rev Bras Hematol Hemoter. 2013;35(6):395-9. doi: 10.5581/1516-8484.20130126.

Abstract

BACKGROUND

So that an improvement in the selection of donors can be achieved and the risk to the recipient of transfused blood can be reduced, prospective donors are submitted to clinical and serological screening.

OBJECTIVE

This study investigated the blood discard rate and the rate of infectious and contagious diseases in blood donors from provincial towns of the state of Paraná, Brazil.

METHODS

This study was an exploratory cross-sectional descriptive investigation with a quantitative approach of donations between January and December 2011.

RESULTS

In the study period the Regional Blood center in Maringá, Brazil received 8337 blood donations from people living in the city and neighboring towns. However, 278 (3.33%) donations were discarded during serological screening owing to one or more positive serological markers. A total of 46.4% of the discarded blood units were confirmed positive by serology with anti-HBc being the most common (66.7%), followed by syphilis (22.5%), HBsAg (4.7%), anti-hepatitis C virus (3.1%), human immunodeficiency virus (1.5%) and Chagas' disease (1.5%). The rate of infectious-contagious diseases that can be transmitted by blood transfusions was 1.55% (129/8337) of the donor population with a frequency of 1.03% for anti-HBc and 0.35% for syphilis.

CONCLUSION

This study demonstrates a high prevalence of the anti-HBc marker in prospective blood donors from provincial towns in the state of Paraná, Brazil.

摘要

背景

为了改进献血者的筛选并降低受血者接受输血的风险,对未来的献血者进行临床和血清学筛查。

目的

本研究调查了巴西巴拉那州各城镇献血者的血液废弃率以及传染病和感染性疾病的发生率。

方法

本研究采用探索性横断面描述性调查,采用定量方法对2011年1月至12月期间的献血情况进行研究。

结果

在研究期间,巴西马林加的地区血液中心收到了来自该市及周边城镇居民的8337份献血。然而,在血清学筛查期间,由于一种或多种血清学标志物呈阳性,有278份(3.33%)献血被废弃。总共46.4%的废弃血液单位经血清学确认呈阳性,其中抗-HBc最为常见(66.7%),其次是梅毒(22.5%)、HBsAg(4.7%)、抗丙型肝炎病毒(3.1%)、人类免疫缺陷病毒(1.5%)和恰加斯病(1.5%)。可通过输血传播的传染病和感染性疾病的发生率在献血人群中为1.55%(129/8337),抗-HBc的发生率为1.03%,梅毒的发生率为0.35%。

结论

本研究表明,在巴西巴拉那州各城镇的未来献血者中,抗-HBc标志物的患病率很高。

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[Syphilis detection using ELISA and VDRL tests on blood donors at the blood center of Guarapuava, State of Paraná].
Rev Soc Bras Med Trop. 2008 Jul-Aug;41(4):428-30. doi: 10.1590/s0037-86822008000400023.
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[Evaluation of the sorologic pre-selection for the hepatitis B virus marker (total anti-HBc) in candidates to blood donation in the State of Acre, 2002].
Rev Soc Bras Med Trop. 2006 Mar-Apr;39(2):179-82. doi: 10.1590/s0037-86822006000200009. Epub 2006 May 5.

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