急性冷暴露对人血浆中促肾上腺皮质激素（ACTH）和锌浓度的影响。

Effect of acute cold exposure on ACTH and zinc concentrations in human plasma.

作者信息

Ohno H, Yahata T, Yamashita K, Kuroshima A

机构信息

Department of Physiology, Asahikawa Medical College, Japan.

出版信息

Jpn J Physiol. 1987;37(4):749-55. doi: 10.2170/jjphysiol.37.749.

DOI:10.2170/jjphysiol.37.749

PMID:2448512

Abstract

Effects of acute cold exposure (10 degrees C for 60 min) on the concentrations of adrenocorticotropin (ACTH) and zinc in plasma were investigated in seven healthy male students. There were no significant changes in total zinc, albumin-bound zinc, and alpha 2-macroglobulin-bound zinc concentrations throughout the experimental period. On the other hand, ACTH concentration increased markedly during cold exposure. In addition, a statistically significant inverse relationship existed between the changes in ACTH and albumin-bound zinc values during the experiment. These results suggest that acute cold exposure produces elevated plasma ACTH levels, with resulting zinc redistribution in the human body.

摘要

对7名健康男学生研究了急性冷暴露（10摄氏度，60分钟）对血浆中促肾上腺皮质激素（ACTH）和锌浓度的影响。在整个实验期间，总锌、白蛋白结合锌和α2-巨球蛋白结合锌的浓度没有显著变化。另一方面，冷暴露期间ACTH浓度显著升高。此外，实验期间ACTH变化与白蛋白结合锌值之间存在统计学上显著的负相关关系。这些结果表明，急性冷暴露会使血浆ACTH水平升高，从而导致人体锌的重新分布。