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健康成年人血清中白蛋白结合锌和α2-巨球蛋白结合锌的浓度。

Albumin bound and alpha 2-macroglobulin bound zinc concentrations in the sera of healthy adults.

作者信息

Foote J W, Delves H T

出版信息

J Clin Pathol. 1984 Sep;37(9):1050-4. doi: 10.1136/jcp.37.9.1050.

Abstract

Reference ranges for albumin bound and alpha 2-macroglobulin bound zinc concentrations have been determined in a study of sera obtained from 134 healthy adults. The concentrations of zinc bound to alpha 2-macroglobulin were remarkably constant with a mean (+/-SD) of 2.4 +/- 0.6 mumol/l; the variations in total serum zinc concentrations were almost entirely accounted for by variations in the zinc associated with albumin. There were no sex related differences in the transport of zinc in serum; neither was this sensitive to the use of oral contraceptives. These data provide a baseline for further investigations into the effects of zinc deficiency on the serum transport of the metal.

摘要

在一项对134名健康成年人血清的研究中,已确定了白蛋白结合锌和α2-巨球蛋白结合锌浓度的参考范围。与α2-巨球蛋白结合的锌浓度非常恒定,平均(±标准差)为2.4±0.6μmol/l;血清总锌浓度的变化几乎完全由与白蛋白相关的锌的变化所解释。血清中锌的转运不存在性别相关差异;这对口服避孕药的使用也不敏感。这些数据为进一步研究锌缺乏对金属血清转运的影响提供了基线。

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