Maman Suzanne, van Rooyen Heidi, Stankard Petra, Chingono Alfred, Muravha Tshifhiwa, Ntogwisangu Jacob, Phakathi Zipho, Srirak Namtip, F Morin Stephen
Department of Health Behavior, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States of America.
Social, Behavioural and Biomedical Interventions Unit, Human Sciences Research Council, Pieternaritzburg, South Africa.
PLoS One. 2014 Jan 29;9(1):e87091. doi: 10.1371/journal.pone.0087091. eCollection 2014.
NIMH Project Accept (HPTN 043) is a community- randomized trial to test the safety and efficacy of a community-level intervention designed to increase testing and lower HIV incidence in Tanzania, Zimbabwe, South Africa and Thailand. The evaluation design included a longitudinal study with community members to assess attitudinal and behavioral changes in study outcomes including HIV testing norms, HIV-related discussions, and HIV-related stigma.
A cohort of 657 individuals across all sites was selected to participate in a qualitative study that involved 4 interviews during the study period. Baseline and 30-month data were summarized according to each outcome, and a qualitative assessment of changes was made at the community level over time.
Members from intervention communities described fewer barriers and greater motivation for testing than those from comparison communities. HIV-related discussions in intervention communities were more grounded in personal testing experiences. A change in HIV-related stigma over time was most pronounced in Tanzania and Zimbabwe. Participants in the intervention communities from these two sites attributed community-level changes in attitudes to project specific activities.
The Project Accept intervention was associated with more favorable social norms regarding HIV testing, more personal content in HIV discussions in all study sites, and qualitative changes in HIV-related stigma in two of five sites.
美国国立精神卫生研究所的“项目接受”(HPTN 043)是一项社区随机试验,旨在测试一项社区层面干预措施的安全性和有效性,该干预措施旨在增加坦桑尼亚、津巴布韦、南非和泰国的检测率并降低艾滋病毒发病率。评估设计包括一项针对社区成员的纵向研究,以评估研究结果中的态度和行为变化,包括艾滋病毒检测规范、与艾滋病毒相关的讨论以及与艾滋病毒相关的耻辱感。
从所有研究地点选取了657名个体组成一个队列,参与一项定性研究,该研究在研究期间进行4次访谈。根据每个结果总结基线和30个月的数据,并对社区层面随时间的变化进行定性评估。
与对照社区的成员相比,干预社区的成员表示检测的障碍更少,检测的积极性更高。干预社区中与艾滋病毒相关的讨论更多地基于个人检测经历。随着时间的推移,与艾滋病毒相关的耻辱感的变化在坦桑尼亚和津巴布韦最为明显。来自这两个地点的干预社区的参与者将社区层面态度的变化归因于项目的特定活动。
“项目接受”干预措施与关于艾滋病毒检测更有利的社会规范、所有研究地点艾滋病毒讨论中更多的个人内容以及五个地点中两个地点与艾滋病毒相关耻辱感的定性变化相关。