Interfaces and Nanomaterials Laboratory, Department of Chemical Engineering, National Institute of Technology, Rourkela 769008, Orissa, India.
Interfaces and Nanomaterials Laboratory, Department of Chemical Engineering, National Institute of Technology, Rourkela 769008, Orissa, India.
Adv Colloid Interface Sci. 2014 Jul;209:8-39. doi: 10.1016/j.cis.2013.12.008. Epub 2014 Jan 14.
Nanoparticles have several exciting applications in different areas and biomedial field is not an exception of that because of their exciting performance in bioimaging, targeted drug and gene delivery, sensors, and so on. It has been found that among several classes of nanoparticles core/shell is most promising for different biomedical applications because of several advantages over simple nanoparticles. This review highlights the development of core/shell nanoparticles-based biomedical research during approximately past two decades. Applications of different types of core/shell nanoparticles are classified in terms of five major aspects such as bioimaging, biosensor, targeted drug delivery, DNA/RNA interaction, and targeted gene delivery.
纳米粒子在不同领域有许多令人兴奋的应用，生物医学领域也不例外，因为它们在生物成像、靶向药物和基因传递、传感器等方面表现出色。研究发现，在几类纳米粒子中，核/壳纳米粒子因其相对于简单纳米粒子的若干优势，在不同的生物医学应用中最有前途。本文综述了过去约二十年中基于核/壳纳米粒子的生物医学研究的发展。不同类型的核/壳纳米粒子的应用根据生物成像、生物传感器、靶向药物传递、DNA/RNA 相互作用和靶向基因传递等五个主要方面进行分类。
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