Cranfield Health Cranfield University Cranfield Bedfordshire, MK43 0AL, UK.
Adv Healthc Mater. 2014 Feb;3(2):160-75. doi: 10.1002/adhm.201300141. Epub 2013 Oct 8.
In the past decades, magnetic nanoparticles (MNPs) have been used in wide range of diverse applications, ranging from separation to sensing. Here, synthesis and applications of functionalized MNPs in the biomedical field are discussed, in particular in drug delivery, imaging, and cancer therapy, highlighting also recent progresses in the development of multifunctional and stimuli-responsive MNPs. The role of their size, composition, and surface functionalization is analyzed, together with their biocompatibility issues.
在过去的几十年中，磁性纳米粒子（MNPs）已经在从分离到传感等广泛的不同应用中得到了应用。本文讨论了功能化 MNPs 在生物医学领域中的应用，特别是在药物传递、成像和癌症治疗方面，同时还强调了多功能和刺激响应性 MNPs 的最新进展。分析了它们的尺寸、组成和表面功能化的作用，以及它们的生物相容性问题。
