Department of Radiation Oncology, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.
Integr Biol (Camb). 2014 Jan;6(1):9-26. doi: 10.1039/c3ib40165k.
Nanoparticles can be engineered with distinctive composition, size, shape, and surface chemistry to enable novel techniques in a wide range of biological applications. The unique properties of nanoparticles and their behavior in biological milieu also enable exciting and integrative approaches to studying fundamental biological questions. This review will provide an overview of various types of nanoparticles and concepts of targeting nanoparticles. We will also discuss the advantages and recent applications of using nanoparticles as tools for drug delivery, imaging, sensing, and for the understanding of basic biological processes.
纳米粒子可以通过独特的组成、大小、形状和表面化学性质进行设计，从而在广泛的生物应用中实现新技术。纳米粒子的独特性质及其在生物环境中的行为也为研究基本生物学问题提供了令人兴奋和综合的方法。本文综述了各种类型的纳米粒子和靶向纳米粒子的概念。我们还将讨论将纳米粒子用作药物输送、成像、传感以及理解基本生物学过程的工具的优势和最新应用。
