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Effect of EPA and vitamin C on superoxide dismutase, glutathione peroxidase, total antioxidant capacity and malondialdehyde in type 2 diabetic patients.二十碳五烯酸（EPA）和维生素C对2型糖尿病患者超氧化物歧化酶、谷胱甘肽过氧化物酶、总抗氧化能力及丙二醛的影响
Oman Med J. 2014 Jan;29(1):39-45. doi: 10.5001/omj.2014.09.
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Total antioxidant capacity and antioxidant enzymes in serum, saliva, and gingival crevicular fluid of preeclamptic women with and without periodontal disease.患和未患牙周病的先兆子痫妇女血清、唾液和龈沟液中的总抗氧化能力及抗氧化酶
J Periodontol. 2007 Aug;78(8):1602-11. doi: 10.1902/jop.2007.060469.
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Beneficial Effects of Endurance Exercise with Rosmarinus officinalis Labiatae Leaves Extract on Blood Antioxidant Enzyme Activities and Lipid Peroxidation in Streptozotocin-Induced Diabetic Rats.迷迭香叶提取物的耐力运动对链脲佐菌素诱导的糖尿病大鼠血液抗氧化酶活性和脂质过氧化的有益作用。
Can J Diabetes. 2015 Jun;39(3):229-34. doi: 10.1016/j.jcjd.2014.11.003. Epub 2015 Feb 4.
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Alternations in free radical erythrocyte-defense mechanisms in streptozotocin induced diabetic rats - effect of antioxidant treatment.链脲佐菌素诱导的糖尿病大鼠红细胞自由基防御机制的改变——抗氧化治疗的作用
Exp Toxicol Pathol. 1999 May;51(3):255-6. doi: 10.1016/s0940-2993(99)80113-4.
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Dietary alpha-tocopherol affects tissue vitamin e and malondialdehyde levels but does not change antioxidant enzymes and fatty acid composition in farmed Atlantic salmon (Salmo salar L.).膳食中的α-生育酚会影响组织中的维生素 E 和丙二醛水平，但不会改变养殖大西洋鲑（Salmo salar L.）中的抗氧化酶和脂肪酸组成。
Int J Vitam Nutr Res. 2013;83(4):238-45. doi: 10.1024/0300-9831/a000166.
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Low doses of eicosapentaenoic acid, docosahexaenoic acid, and hypolipidemic eicosapentaenoic acid derivatives have no effect on lipid peroxidation in plasma.低剂量的二十碳五烯酸、二十二碳六烯酸和降血脂的二十碳五烯酸衍生物对血浆中的脂质过氧化没有影响。
Lipids. 1998 Nov;33(11):1131-7. doi: 10.1007/s11745-998-0315-6.
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Dysregulation of hepatic superoxide dismutase, catalase and glutathione peroxidase in diabetes: response to insulin and antioxidant therapies.糖尿病中肝脏超氧化物歧化酶、过氧化氢酶和谷胱甘肽过氧化物酶的失调：对胰岛素和抗氧化疗法的反应。
Clin Exp Hypertens. 2004 Jan;26(1):43-53. doi: 10.1081/ceh-120027330.
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Pentose phosphate pathway, glutathione-dependent enzymes and antioxidant defense during oxidative stress in diabetic rodent brain and peripheral organs: effects of stobadine and vitamin E.糖尿病啮齿动物脑和外周器官氧化应激期间的磷酸戊糖途径、谷胱甘肽依赖性酶与抗氧化防御：司他定和维生素E的作用
Neurochem Res. 2003 Jun;28(6):815-23. doi: 10.1023/a:1023202805255.
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Serum and dietary antioxidant status is associated with lower prevalence of the metabolic syndrome in a study in Shanghai, China.在中国上海的一项研究中，血清和膳食抗氧化状态与代谢综合征的较低患病率相关。
Asia Pac J Clin Nutr. 2013;22(1):60-8. doi: 10.6133/apjcn.2013.22.1.06.
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The Role of Diet in Modulating Inflammation and Oxidative Stress in Rheumatoid Arthritis, Ankylosing Spondylitis, and Psoriatic Arthritis.饮食在调节类风湿关节炎、强直性脊柱炎和银屑病关节炎中的炎症和氧化应激中的作用
Nutrients. 2025 May 7;17(9):1603. doi: 10.3390/nu17091603.
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Correlation between omega-3 intake and the incidence of diabetic retinopathy based on NHANES from 2005 to 2008.基于 2005 年至 2008 年 NHANES 数据的 ω-3 摄入量与糖尿病视网膜病变发生率的相关性。
Acta Diabetol. 2024 Aug;61(8):997-1005. doi: 10.1007/s00592-024-02267-4. Epub 2024 Apr 16.
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Vitamin C as Scavenger of Reactive Oxygen Species during Healing after Myocardial Infarction.维生素 C 作为心肌梗死后愈合过程中活性氧物质的清除剂。
Int J Mol Sci. 2024 Mar 7;25(6):3114. doi: 10.3390/ijms25063114.
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Vitamin C supplementation lowers advanced glycation end products (AGEs) and malondialdehyde (MDA) in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled clinical trial.补充维生素C可降低2型糖尿病患者的晚期糖基化终末产物（AGEs）和丙二醛（MDA）：一项随机、双盲、安慰剂对照临床试验。
Food Sci Nutr. 2023 Jun 30;11(10):5967-5977. doi: 10.1002/fsn3.3530. eCollection 2023 Oct.
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Ascorbic Acid vs Calcitriol in Influencing Monocyte Chemoattractant Protein-1, Nitric Oxide, Superoxide Dismutase, as Markers of Endothelial Dysfunction: In Vivo Study in Atherosclerosis Rat Model.抗坏血酸与骨化三醇对单核细胞趋化蛋白-1、一氧化氮、超氧化物歧化酶的影响及其对血管内皮功能障碍标志物的影响：动脉粥样硬化大鼠模型的体内研究。
Vasc Health Risk Manag. 2023 Mar 12;19:139-144. doi: 10.2147/VHRM.S401521. eCollection 2023.
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Opioids and Vitamin C: Known Interactions and Potential for Redox-Signaling Crosstalk.阿片类药物与维生素C：已知的相互作用及氧化还原信号串扰的可能性
Antioxidants (Basel). 2022 Jun 27;11(7):1267. doi: 10.3390/antiox11071267.
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Efficacy of High-Dose Vitamin C Infusion on Outcomes in Sepsis Requiring Mechanical Ventilation: A Double-Blind Randomized Controlled Trial.大剂量维生素C输注对需要机械通气的脓毒症患者预后的疗效：一项双盲随机对照试验
Anesthesiol Res Pract. 2022 Jul 15;2022:4057215. doi: 10.1155/2022/4057215. eCollection 2022.
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Anti-neoplastic action of Cimetidine/Vitamin C on histamine and the PI3K/AKT/mTOR pathway in Ehrlich breast cancer.西咪替丁/维生素 C 对组氨酸和 PI3K/AKT/mTOR 通路在艾氏腹水癌中的抗肿瘤作用。
Sci Rep. 2022 Jul 7;12(1):11514. doi: 10.1038/s41598-022-15551-6.
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Could nutrient supplements provide additional glycemic control in diabetes management? A systematic review and meta-analysis of randomized controlled trials of as an add-on nutritional supplementation therapy.营养素补充剂能否为糖尿病管理提供额外的血糖控制？作为附加营养补充治疗的随机对照试验的系统评价和荟萃分析。
Arch Pharm Res. 2022 Mar;45(3):185-204. doi: 10.1007/s12272-022-01374-6. Epub 2022 Mar 18.
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Protective Effects and Molecular Signaling of n-3 Fatty Acids on Oxidative Stress and Inflammation in Retinal Diseases.n-3脂肪酸对视网膜疾病氧化应激和炎症的保护作用及分子信号传导
Antioxidants (Basel). 2020 Sep 26;9(10):920. doi: 10.3390/antiox9100920.
本文引用的文献
1
Effects of EPA and Vitamin E on Serum Enzymatic Antioxidants and Peroxidation Indices in Patients with Type II Diabetes Mellitus.二十碳五烯酸（EPA）与维生素E对II型糖尿病患者血清酶抗氧化剂及过氧化指标的影响
Iran J Public Health. 2010;39(3):82-91. Epub 2010 Sep 30.
2
Effect of eicosapentaenoic Acid (EPA) and vitamin e on the blood levels of inflammatory markers, antioxidant enzymes, and lipid peroxidation in Iranian basketball players.二十碳五烯酸（EPA）和维生素E对伊朗篮球运动员血液中炎症标志物、抗氧化酶水平及脂质过氧化的影响。
Iran J Public Health. 2010;39(1):15-21. Epub 2010 Mar 31.
3
General and gender characteristics of type 2 diabetes mellitus among the younger and older age groups.年轻和老年人群中2型糖尿病的一般特征和性别特征。
Oman Med J. 2012 Sep;27(5):375-82. doi: 10.5001/omj.2012.94.
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Vitamin C and fibre consumption from fruits and vegetables improves oxidative stress markers in healthy young adults.水果和蔬菜中的维生素 C 和膳食纤维的摄入可改善健康年轻成年人的氧化应激标志物。
Br J Nutr. 2012 Apr;107(8):1119-27. doi: 10.1017/S0007114511004235. Epub 2011 Sep 7.
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Effect of consumption of tomato juice enriched with n-3 polyunsaturated fatty acids on the lipid profile, antioxidant biomarker status, and cardiovascular disease risk in healthy women.富含 n-3 多不饱和脂肪酸的番茄汁对健康女性血脂谱、抗氧化生物标志物状态和心血管疾病风险的影响。
Eur J Nutr. 2012 Jun;51(4):415-24. doi: 10.1007/s00394-011-0225-0. Epub 2011 Jul 14.
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Ascorbate-dependent decrease of the mucosal immune inflammatory response to gliadin in coeliac disease patients.在乳糜泻患者中，抗坏血酸盐依赖性降低对麦醇溶蛋白的黏膜免疫炎症反应。
Allergol Immunopathol (Madr). 2012 Jan-Feb;40(1):3-8. doi: 10.1016/j.aller.2010.11.003. Epub 2011 Mar 21.
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Sirt3-mediated deacetylation of evolutionarily conserved lysine 122 regulates MnSOD activity in response to stress.Sirt3 介导的赖氨酸 122 的去乙酰化作用调节 MnSOD 活性以响应应激。
Mol Cell. 2010 Dec 22;40(6):893-904. doi: 10.1016/j.molcel.2010.12.013.
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The determination of ascorbic acid in small amounts of blood serum.少量血清中抗坏血酸的测定
J Biol Chem. 1945;160:609-15.
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The fat-1 transgene in mice increases antioxidant potential, reduces pro-inflammatory cytokine levels, and enhances PPAR-gamma and SIRT-1 expression on a calorie restricted diet.在限制热量摄入的饮食中，脂肪-1 转基因小鼠增加了抗氧化能力，降低了促炎细胞因子水平，并增强了过氧化物酶体增殖物激活受体-γ和 SIRT-1 的表达。
Oxid Med Cell Longev. 2009 Nov-Dec;2(5):307-16. doi: 10.4161/oxim.2.5.9579.
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Attenuation of age- and sucrose-induced insulin resistance and syndrome X by a synergistic antioxidant cocktail: the AMIS syndrome and HISS hypothesis.协同抗氧化鸡尾酒对年龄和蔗糖诱导的胰岛素抵抗和综合征 X 的衰减：AMIS 综合征和 HISS 假说。
Can J Physiol Pharmacol. 2010 Mar;88(3):313-23. doi: 10.1139/Y09-130.
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