Choi Eun-Joo, Kim Kyae-Hyung, Koh Young-Jin, Lee Jee-Sun, Lee Dong-Ryul, Park Sang Min
Department of Family Medicine, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
Department of Family Medicine, Wonkwang University Sanbon Hospital, Wonkwang University College of Medicine, Gunpo, Korea.
Korean J Fam Med. 2014 Jan;35(1):11-8. doi: 10.4082/kjfm.2014.35.1.11. Epub 2014 Jan 23.
Although Asian people are known to have lower bone mass than that of Caucasians, little is known about coffee-associated bone health in Asian. This study aimed to assess the relationship between coffee consumption and bone mineral density (BMD) in Korean premenopausal women.
Data were obtained from the Fourth Korea National Health and Nutrition Examination Survey 2008-2009. The study population consisted of 1,761 Korean premenopausal women (mean age 36 years) who were measured for lumbar spine and femoral neck BMD and who completed a standardized questionnaire about coffee intake frequency. We excluded the participants who took hormone replacement therapy or medication for osteoporosis. The cross-sectional relationship between coffee consumption and impaired bone health (osteopenia or osteoporosis) was investigated by bone densitometry.
Coffee consumption showed no significant association with BMD of either femoral neck or lumbar spine, independent of other factors. The adjusted odds ratios for BMD for those who consumed once in a day, twice a day and three times a day were 0.94 (0.70-1.26), 0.93 (0.67-1.28), and 1.02 (0.69-1.50), respectively (P for trend = 0.927).
This study does not support the idea that coffee is a risk factor for impaired bone health in Korean premenopausal women.
虽然已知亚洲人的骨量低于白种人，但关于咖啡与亚洲人骨骼健康的关系却知之甚少。本研究旨在评估韩国绝经前女性咖啡摄入量与骨密度（BMD）之间的关系。
数据来自2008 - 2009年第四次韩国国家健康与营养检查调查。研究人群包括1761名韩国绝经前女性（平均年龄36岁），她们接受了腰椎和股骨颈骨密度测量，并完成了一份关于咖啡摄入频率的标准化问卷。我们排除了接受激素替代疗法或骨质疏松症药物治疗的参与者。通过骨密度测定法研究了咖啡摄入量与骨骼健康受损（骨质减少或骨质疏松）之间的横断面关系。
独立于其他因素，咖啡摄入量与股骨颈或腰椎的骨密度均无显著关联。每天饮用一次、两次和三次咖啡的人群骨密度调整后的优势比分别为0.94（0.70 - 1.26）、0.93（0.67 - 1.28）和1.02（0.69 - 1.50）（趋势P值 = 0.927）。
本研究不支持咖啡是韩国绝经前女性骨骼健康受损风险因素这一观点。
