Section of Geriatrics, Department of Internal Medicine, School of Medicine, Yale University, New Haven, Connecticut.
J Am Geriatr Soc. 2014 Mar;62(3):476-81. doi: 10.1111/jgs.12685. Epub 2014 Feb 11.
To estimate the rate of restricting fatigue in community-living older adults and to determine whether the rates differ according to age, sex, race, physical frailty, and depression.
Prospective cohort study.
Greater New Haven, Connecticut.
Nondisabled community-living older men and women aged 70 and older (N = 754).
Restricting fatigue was defined as staying in bed for at least half the day and/or cutting down on one's usual activities because of fatigue for 3 consecutive months or longer. Physical frailty was defined on the basis of slow gait speed, and depression was assessed using the Center for Epidemiologic Studies Depression Scale.
During a median follow-up of 111 months, the cumulative incidence of restricting fatigue was 31.1% for men and 42.1% for women. The overall incidence rate of restricting fatigue was 6.7 per 1,000 person-months (7.8 for women and 4.4 for men, P < .001), which did not differ according to race. Rates were higher in persons who were physically frail than those who were not (P < .001), in those who were depressed than those who were not (P < .001), and in persons aged 75 to 79 and 80 to 84 than those aged 70 to 74 (both P < .01) but not in those aged 85 and older. Of the 459 episodes of restricting fatigue, the median duration was 3 months, which did not differ according to age, sex, race, physical frailty, or depression.
Restricting fatigue is common in community-living older adults. Women, individuals aged 75 to 84, and individuals with physical frailty or depression had higher rates of restricting fatigue than their respective counterparts.
估计社区居住的老年人群中限制疲劳的发生率,并确定其发生率是否因年龄、性别、种族、身体虚弱和抑郁而有所不同。
前瞻性队列研究。
康涅狄格州纽黑文市。
70 岁及以上的非残疾社区居住的老年男女(N=754)。
限制疲劳的定义为因疲劳连续 3 个月或更长时间卧床至少半天和/或减少日常活动。身体虚弱是根据缓慢的步态速度来定义的,抑郁是使用流行病学研究中心抑郁量表评估的。
在中位随访 111 个月期间,男性限制疲劳的累积发生率为 31.1%,女性为 42.1%。限制疲劳的总发生率为每 1000 人-月 6.7 例(女性为 7.8 例,男性为 4.4 例,P<.001),且与种族无关。身体虚弱的人比身体不虚弱的人发生率更高(P<.001),抑郁的人比不抑郁的人发生率更高(P<.001),75 至 79 岁和 80 至 84 岁的人比 70 至 74 岁的人发生率更高(均 P<.01),但 85 岁及以上的人则不然。在 459 例限制疲劳发作中,中位持续时间为 3 个月,与年龄、性别、种族、身体虚弱或抑郁无关。
限制疲劳在社区居住的老年人群中很常见。女性、75 至 84 岁的人群以及身体虚弱或抑郁的个体比相应的个体有更高的限制疲劳发生率。