National Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
National Laboratory of Plant Molecular Genetics, Shanghai Institute of Plant Physiology and Ecology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.
Curr Top Dev Biol. 2014;108:1-33. doi: 10.1016/B978-0-12-391498-9.00009-7.
Plants have evolved powerful regeneration abilities to recover from damage. Studies on plant regeneration are of high significance as the underlying mechanisms of plant regeneration are not only linking to the fundamental researches in many fields but also to the development of widely used plant biotechnology. Higher plants show three main types of regeneration: tissue regeneration, de novo organogenesis, and somatic embryogenesis. In this review, we summarize recent research on plant regeneration, mainly focusing on Arabidopsis thaliana and moss. New data suggest that plant hormones trigger regeneration and that several key transcription factors respond to hormone signals to determine cell-fate transition. Cell-fate transition requires genome-wide changes in gene expression, which are regulated via epigenetic pathways. Certain epigenetic factors may be recruited by transcription factors to relocate to new loci and regulate gene expression. Cross talk among hormone signaling, transcription factors, and epigenetic factors is involved in different types of plant regeneration, suggesting that elegant and complex regulatory mechanisms control which type of regeneration is triggered in plants under different circumstances. Since regeneration is initiated by wounding, identification of the wound signal is an important objective for future research.
植物已经进化出强大的再生能力，以从损伤中恢复。研究植物再生具有重要意义，因为植物再生的潜在机制不仅与许多领域的基础研究有关，而且与广泛应用的植物生物技术的发展有关。高等植物表现出三种主要的再生方式：组织再生、从头器官发生和体细胞胚胎发生。在这篇综述中，我们总结了植物再生的最新研究进展，主要集中在拟南芥和苔藓上。新的数据表明，植物激素触发再生，并且几个关键的转录因子响应激素信号来决定细胞命运的转变。细胞命运的转变需要全基因组的基因表达变化，这些变化通过表观遗传途径进行调节。某些表观遗传因子可能被转录因子募集，重新定位到新的基因座，并调节基因表达。激素信号、转录因子和表观遗传因子之间的串扰参与了不同类型的植物再生，这表明在不同的情况下，复杂的调控机制控制着哪种类型的再生在植物中被触发。由于再生是由创伤引发的，因此鉴定创伤信号是未来研究的一个重要目标。
