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高危患者出院后虚拟病房对再入院或死亡的影响:一项随机临床试验。

Effect of a postdischarge virtual ward on readmission or death for high-risk patients: a randomized clinical trial.

机构信息

Department of Medicine, University of Toronto, Toronto, Ontario, Canada2Institute of Health Policy, Management and Evaluation, University of Toronto, Toronto3Department of Medicine, St Michael's Hospital, Toronto4Li Ka Shing Knowledge Institute of St Mich.

Department of Medicine, University of Toronto, Toronto, Ontario, Canada6Department of Medicine, Women's College Hospital, Toronto.

出版信息

JAMA. 2014 Oct 1;312(13):1305-12. doi: 10.1001/jama.2014.11492.

Abstract

IMPORTANCE

Hospital readmissions are common and costly, and no single intervention or bundle of interventions has reliably reduced readmissions. Virtual wards, which use elements of hospital care in the community, have the potential to reduce readmissions, but have not yet been rigorously evaluated.

OBJECTIVE

To determine whether a virtual ward-a model of care that uses some of the systems of a hospital ward to provide interprofessional care for community-dwelling patients-can reduce the risk of readmission in patients at high risk of readmission or death when being discharged from hospital.

DESIGN, SETTING, AND PATIENTS: High-risk adult hospital discharge patients in Toronto were randomly assigned to either the virtual ward or usual care. A total of 1923 patients were randomized during the course of the study: 960 to the usual care group and 963 to the virtual ward group. The first patient was enrolled on June 29, 2010, and follow-up was completed on June 2, 2014.

INTERVENTIONS

Patients assigned to the virtual ward received care coordination plus direct care provision (via a combination of telephone, home visits, or clinic visits) from an interprofessional team for several weeks after hospital discharge. The interprofessional team met daily at a central site to design and implement individualized management plans. Patients assigned to usual care typically received a typed, structured discharge summary, prescription for new medications if indicated, counseling from the resident physician, arrangements for home care as needed, and recommendations, appointments, or both for follow-up care with physicians as indicated.

MAIN OUTCOMES AND MEASURES

The primary outcome was a composite of hospital readmission or death within 30 days of discharge. Secondary outcomes included nursing home admission and emergency department visits, each of the components of the primary outcome at 30 days, as well as each of the outcomes (including the composite primary outcome) at 90 days, 6 months, and 1 year.

RESULTS

There were no statistically significant between-group differences in the primary or secondary outcomes at 30 or 90 days, 6 months, or 1 year. The primary outcome occurred in 203 of 959 (21.2%) of the virtual ward patients and 235 of 956 (24.6%) of the usual care patients (absolute difference, 3.4%; 95% CI, -0.3% to 7.2%; P = .09). There were no statistically significant interactions to indicate that the virtual ward model of care was more or less effective in any of the prespecified subgroups.

CONCLUSIONS AND RELEVANCE

In a diverse group of high-risk patients being discharged from the hospital, we found no statistically significant effect of a virtual ward model of care on readmissions or death at either 30 days or 90 days, 6 months, or 1 year after hospital discharge.

TRIAL REGISTRATION

clinicaltrials.gov Identifier: NCT01108172.

摘要

重要性

医院再入院是常见且代价高昂的,没有单一的干预措施或干预措施组合能够可靠地降低再入院率。虚拟病房利用了社区医院护理的要素,具有降低再入院率的潜力,但尚未经过严格评估。

目的

确定虚拟病房——一种利用医院病房系统为社区居住的患者提供跨专业护理的护理模式——是否可以降低高危再入院或死亡的出院患者的再入院风险。

设计、地点和患者:多伦多高危成年医院出院患者被随机分配到虚拟病房或常规护理组。在研究过程中共有 1923 名患者被随机分组:960 名患者分入常规护理组,963 名患者分入虚拟病房组。第一个患者于 2010 年 6 月 29 日入组,随访于 2014 年 6 月 2 日完成。

干预措施

分配到虚拟病房的患者在出院后数周内接受跨专业团队的护理协调加直接护理(通过电话、家访或诊所访问的组合)。跨专业团队每天在一个中心地点开会,设计和实施个体化管理计划。分配到常规护理组的患者通常会收到一份打印的、结构化的出院小结、如有需要的新药物处方、住院医师的咨询、按需安排家庭护理、以及根据需要为后续医生就诊预约或推荐。

主要结果和措施

主要结果是出院后 30 天内的医院再入院或死亡的复合结局。次要结局包括入住疗养院和急诊就诊,每个结局都在 30 天进行评估,以及每个结局(包括主要复合结局)在 90 天、6 个月和 1 年时进行评估。

结果

在 30 天或 90 天、6 个月或 1 年时,两组之间的主要或次要结局均无统计学意义上的差异。虚拟病房组 959 例患者中有 203 例(21.2%)和常规护理组 956 例患者中有 235 例(24.6%)发生了主要结局(绝对差值,3.4%;95%CI,-0.3%至 7.2%;P=0.09)。没有统计学意义上的交互作用表明虚拟病房护理模式在任何预先指定的亚组中更有效或更无效。

结论和相关性

在一组来自不同医院的高危患者中,我们发现虚拟病房护理模式在出院后 30 天或 90 天、6 个月或 1 年时,在再入院或死亡方面对患者没有统计学意义上的影响。

试验注册

clinicaltrials.gov 标识符:NCT01108172。

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