Mousavi Ateke, Vafa Mohammadreza, Neyestani Tirang, Khamseh Mohammadebrahim, Hoseini Fatemeh
Department of Cellular and Molecular Nutrition, School of Nutrition and Dietetics, Tehran University of Medical Sciences, Tehran, Iran.
Department of Nutrition, School of Public Health, Iran University of Medical Sciences, Tehran, Iran ; Department of Endocrinology, School of Public Health, Iran University of Medical Sciences, Tehran, Iran.
J Res Med Sci. 2013 Dec;18(12):1080-6.
This study aims at investigating the possible effects of different daily doses of green tea (GT) intake for eight weeks on certain anthropometric, metabolic, and oxidative stress biomarkers of diabetic patients.
This randomized clinical trial included 63 patients with type 2 diabetes (30 males and 33 females). After a two-week run-in period without green tea, they were randomly assigned into one of the three groups, with a different daily intake of green tea; four cups of green tea per day (n = 24), two cups of green tea per day (n = 25), and the control group (n = 14) with no green tea intake for two months. At baseline and after the intervention, blood tests, dietary, and anthropometric variables were assessed. The patients were instructed to maintain their usual dietary intake and normal physical activity.
Consumption of four cups of GT per day caused a significant decrease in body weight (73.2 to 71.9) (P < 0.001), body mass index (27.4 to 26.9) (P < 0.001), waist circumference (95.8 to 91.5) (P < 0.001), and systolic blood pressure (126.2 to 118.6) (P < 0.05) in this group. No significant change was seen in the other groups and between group comparisons. The metabolic and oxidative stress parameters did not show any significant differences within and between groups.
Drinking four cups of green tea led to a significant reduction in weight and systolic blood pressure.
本研究旨在调查连续八周每天摄入不同剂量绿茶对糖尿病患者某些人体测量学、代谢和氧化应激生物标志物的可能影响。
这项随机临床试验纳入了63例2型糖尿病患者(30例男性和33例女性)。在为期两周的无绿茶导入期后,他们被随机分为三组之一,每组每天摄入不同剂量的绿茶;每天四杯绿茶(n = 24),每天两杯绿茶(n = 25),以及对照组(n = 14),对照组两个月不摄入绿茶。在基线期和干预后,评估血液检查、饮食和人体测量学变量。患者被要求保持其通常的饮食摄入量和正常的身体活动。
每天饮用四杯绿茶的这组患者体重显著下降(从73.2降至71.9)(P < 0.001),体重指数显著下降(从27.4降至26.9)(P < 0.001),腰围显著下降(从95.8降至91.5)(P < 0.001),收缩压显著下降(从126.2降至118.6)(P < 0.05)。其他组以及组间比较均未观察到显著变化。代谢和氧化应激参数在组内和组间均未显示出任何显著差异。
饮用四杯绿茶可导致体重和收缩压显著降低。