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CiteAb:一个可搜索的抗体数据库,该数据库根据抗体被引用的次数进行排名。

CiteAb: a searchable antibody database that ranks antibodies by the number of times they have been cited.

作者信息

Helsby Matthew A, Leader Paul M, Fenn Joe R, Gulsen Tulay, Bryant Chris, Doughton Gail, Sharpe Ben, Whitley Paul, Caunt Christopher J, James Katrina, Pope Adam D, Kelly Dave H, Chalmers Andrew D

机构信息

Department of Biology and Biochemistry, University of Bath, Bath BA2 7AY, UK.

出版信息

BMC Cell Biol. 2014 Feb 14;15:6. doi: 10.1186/1471-2121-15-6.

Abstract

BACKGROUND

Research antibodies are used by thousands of scientists working in diverse disciplines, but it is common to hear concerns about antibody quality. This means that researchers need to carefully choose the antibodies they use to avoid wasting time and money. A well accepted way of selecting a research antibody is to identify one which has been used previously, where the associated data has been peer-reviewed and the results published.

DESCRIPTION

CiteAb is a searchable database which ranks antibodies by the number of times they have been cited. This allows researchers to easily find antibodies that have been used in peer-reviewed publications and the accompanying citations are listed, so users can check the data contained within the publications. This makes CiteAb a useful resource for identifying antibodies for experiments and also for finding information to demonstrate antibody validation. The database currently contains 1,400,000 antibodies which are from 90 suppliers, including 87 commercial companies and 3 academic resources. Associated with these antibodies are 140,000 publications which provide 306,000 antibody citations. In addition to searching, users can also browse through the antibodies and add their own publications to the CiteAb database.

CONCLUSIONS

CiteAb provides a new way for researchers to find research antibodies that have been used successfully in peer-reviewed publications. It aims to assist these researchers and will hopefully help promote progress in many areas of life science research.

摘要

背景

数千名从事不同学科研究的科学家都会使用研究用抗体,但人们经常会听到对抗体质量的担忧。这意味着研究人员需要谨慎选择他们使用的抗体,以免浪费时间和金钱。一种广为接受的选择研究用抗体的方法是找到一种之前已被使用过的抗体,其相关数据已经过同行评审且结果已发表。

描述

CiteAb是一个可搜索的数据库,它根据抗体被引用的次数对其进行排名。这使得研究人员能够轻松找到在同行评审出版物中被使用过的抗体,并且会列出相关的引用文献,这样用户就可以查看出版物中包含的数据。这使得CiteAb成为识别用于实验的抗体以及查找用于证明抗体验证的信息的有用资源。该数据库目前包含来自90家供应商的140万种抗体,其中包括87家商业公司和3家学术资源机构。与这些抗体相关的有14万篇出版物,提供了30.6万次抗体引用。除了搜索功能外,用户还可以浏览抗体并将自己的出版物添加到CiteAb数据库中。

结论

CiteAb为研究人员提供了一种新方法,以找到在同行评审出版物中成功使用过的研究用抗体。它旨在帮助这些研究人员,并有望促进生命科学研究许多领域的进展。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/17c2/3928599/e5a413bc603c/1471-2121-15-6-1.jpg

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