Whipple S C, Parker E S, Noble E P
Alcohol Research Center, University of California, Los Angeles 90024-1759.
J Stud Alcohol. 1988 May;49(3):240-4. doi: 10.15288/jsa.1988.49.240.
Prepubescent boys and their recovering alcoholic fathers exhibited an Atypical Neurocognitive Profile consisting of (1) a reduction in amplitude of the late positive complex (LPC) of the event-related potential (ERP) during a complex visual discrimination task, and (2) reduced visuoperceptual performance evidenced by significantly lower scores on the Object Assembly, Block Design and Picture Completion subtests of the WISC-R and the Embedded Figures Test. Low LPC amplitudes were significantly correlated with poorer visuoperceptual performance. This Atypical Neurocognitive Profile may represent a marker for alcoholism.
青春期前男孩及其正在戒酒康复的父亲表现出一种非典型神经认知特征，包括：（1）在复杂视觉辨别任务中，事件相关电位（ERP）的晚期正复合波（LPC）振幅降低；（2）视觉感知能力下降，这在韦氏儿童智力量表修订版（WISC - R）的物体拼凑、积木图案和图片完成子测试以及嵌入式图形测试中得分显著较低得到证明。低LPC振幅与较差的视觉感知能力显著相关。这种非典型神经认知特征可能代表酗酒的一个标志。
