Cervical lesions in patients with malignant melanoma.

Koilocytes were found in the cervical epithelium in association with cervical intra-epithelial neoplasia in 8 out of 9 cases of malignant melanoma. This suggests that the cervical lesion in them was of viral origin. In 62 women with malignant melanoma but without cervical atypia there was also an excess of koilocytosis compared with controls with neither lesion. These findings point to the possibility that human papilloma virus infection may also be involved in the development of malignant melanoma, as it has been shown to be in cervical intra-epithelial neoplasia.