Gillberg Neuropsychiatry Centre, Sahlgrenska Academy, Gothenburg University, Göteborg, Sweden,
J Autism Dev Disord. 2014 Aug;44(8):2074-6. doi: 10.1007/s10803-014-2070-5.
We draw attention to a number of important considerations in the arguments about screening and outcome of intervention in children with autism and other developmental disorders. Autism screening in itself never provides a final clinical diagnosis, but may well identify developmental deviations indicative of autism-or of other developmental disorders-that should lead to referral for further clinical assessment. Decisions regarding population or clinic screening cannot be allowed to be based on the fact that prospective longitudinal RCT designs over decades could never be performed in complex developmental disorders. We propose an alternative approach. Early screening for autism and other developmental disorders is likely to be of high societal importance and should be promoted and rigorously evaluated.
我们提请注意在自闭症和其他发育障碍儿童的筛查和干预结果的争论中的一些重要考虑因素。自闭症筛查本身并不能提供最终的临床诊断，但很可能会发现表明自闭症或其他发育障碍的发育偏差，这些偏差应该导致进一步的临床评估。不能基于这样一个事实，即复杂的发育障碍不可能在几十年内进行前瞻性纵向 RCT 设计，从而允许对人群或临床筛查的决策进行基于这种事实的决策。我们提出了一种替代方法。早期筛查自闭症和其他发育障碍可能具有很高的社会重要性，应该得到推广和严格评估。
