Li Qian, Khatibi Nikan, Zhang John H
Department of Neurology, The Fifth People's Hospital of Chongqing, Chongqing, China, 400062.
Transl Stroke Res. 2014 Apr;5(2):163-6. doi: 10.1007/s12975-014-0335-0. Epub 2014 Feb 25.
This perspective commentary summarized the stroke pathophysiology evolution, especially the focus in the past on neuroprotection and neurovascular protection and highlighted the newer term for stroke pathophysiology: vascular neural network. Emphasis is on the role of venules and veins after an acute stroke and as potential treatment targets. Vein drainage may contribute to the acute phase of brain edema and the outcomes of stroke patients.
这篇观点评论总结了中风病理生理学的演变,尤其是过去对神经保护和神经血管保护的关注,并强调了中风病理生理学的新术语:血管神经网络。重点是急性中风后小静脉和静脉的作用以及作为潜在治疗靶点的情况。静脉引流可能导致脑水肿的急性期和中风患者的预后。