Castillo-Carniglia Álvaro, Kaufman Jay S, Pino Paulina
Doctoral Program in Public Health, University of Chile, Av. Independencia 939, Santiago, Chile; Research Department, National Service for Prevention and Rehabilitation of Drug and Alcohol Consumption (SENDA), Agustinas 1235, Santiago, Chile.
Department of Epidemiology, Biostatistics and Occupational Health, McGill University, 1020 Pine Ave West, Montreal, Quebec, Canada.
Drug Alcohol Depend. 2014 Apr 1;137:129-36. doi: 10.1016/j.drugalcdep.2014.01.020. Epub 2014 Feb 12.
Little is known about the association between alcohol-attributable mortality and small area socioeconomic variables when considering causes both wholly and partially attributable to alcohol.
An ecological study was conducted of the entire Chilean population aged 15 and older in 345 municipalities nationwide between 2004 and 2009. Deaths were attributed to alcohol consumption either wholly or partially, along with the estimated attributable fractions for each specified cause. Each municipality was characterized according to its average income and educational attainment. Estimates of the ecological associations were produced using a hierarchical Bayesian model, separating out deaths caused by alcohol and dividing them into seven groups of causes.
Alcohol-attributable mortality risk showed an inverse association with income and education at the ecological level. A one-quintile increase in income was associated with an average decrease in risk of 10% (CI 95%: 10-20%) for cardiovascular deaths, 8% (6-10%) for intentional injuries and 7% (3-11%) for unintentional injuries. No associations were found between deaths due to cancers and other causes with income and education.
Municipalities with lower income and education have higher risk of alcohol-attributable mortality in Chile.
在考虑完全和部分归因于酒精的病因时,关于酒精所致死亡率与小区域社会经济变量之间的关联,人们了解甚少。
对2004年至2009年期间全国345个城市中15岁及以上的智利全体人口进行了一项生态学研究。死亡被归因于全部或部分饮酒,以及每种特定病因的估计归因比例。每个城市根据其平均收入和教育程度进行特征描述。使用分层贝叶斯模型得出生态学关联的估计值,将酒精导致的死亡分离出来并分为七组病因。
在生态学层面,酒精所致死亡率风险与收入和教育呈负相关。收入每增加一个五分位数,心血管疾病死亡风险平均降低10%(95%置信区间:10 - 20%),故意伤害死亡风险降低8%(6 - 10%),意外伤害死亡风险降低7%(3 - 11%)。未发现癌症和其他病因导致的死亡与收入和教育之间存在关联。
在智利,收入和教育水平较低的城市酒精所致死亡率风险较高。