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用于生物医学应用的碳基纳米复合材料。

Carbon-based nanocomposites for biomedical applications.

作者信息

Shin Minkyu, Lim Joungpyo, Park Yongseon, Lee Ji-Young, Yoon Jinho, Choi Jeong-Woo

机构信息

Department of Chemical & Biomolecular Engineering, Sogang University 35 Baekbeom-ro, Mapo-gu Seoul 04107 Republic of Korea

Department of Biomedical-Chemical Engineering, The Catholic University of Korea 43 Jibong-ro, Wonmi-gu Bucheon-si Gyeonggi-do 14662 Republic of Korea

出版信息

RSC Adv. 2024 Feb 28;14(10):7142-7156. doi: 10.1039/d3ra08946k. eCollection 2024 Feb 21.

DOI:10.1039/d3ra08946k
PMID:38419681
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10900039/
Abstract

Carbon nanomaterials have attracted significant attention in the biomedical field, including for biosensing, drug delivery, and tissue engineering applications. Based on their inherent properties such as their unique structure and high conductivity, carbon nanomaterials can overcome the current limitations in biomedical research such as poor stability of biomolecules, low sensitivity and selectivity of biosensors, and difficulty in precise drug delivery. In addition, recently, several novel nanomaterials have been integrated with carbon nanomaterials to develop carbon-based nanocomposites for application in biomedical research. In this review, we discuss recent studies on carbon-based nanocomposites and their biomedical applications. First, we discuss the representative carbon nanomaterials and nanocomposites composed of carbon and other novel nanomaterials. Next, applications of carbon nanomaterials and nanocomposites in the biomedical field are discussed according to topics in the biomedical field. We have discussed the recent studies on biosensors, drug delivery, and tissue engineering. In conclusion, we believe that this review provides the potential and applicability of carbon nanomaterials and their nanocomposites and suggests future directions of the application of carbon-based nanocomposites in biomedical applications.

摘要

碳纳米材料在生物医学领域引起了广泛关注,包括生物传感、药物递送和组织工程应用等方面。基于其固有特性,如独特的结构和高导电性,碳纳米材料能够克服生物医学研究中当前存在的局限性,如生物分子稳定性差、生物传感器灵敏度和选择性低以及精确药物递送困难等问题。此外,近年来,几种新型纳米材料已与碳纳米材料结合,开发出用于生物医学研究的碳基纳米复合材料。在本综述中,我们讨论了关于碳基纳米复合材料及其生物医学应用的最新研究。首先,我们讨论了由碳和其他新型纳米材料组成的代表性碳纳米材料和纳米复合材料。接下来,根据生物医学领域的主题,讨论了碳纳米材料和纳米复合材料在生物医学领域的应用。我们已经讨论了关于生物传感器、药物递送和组织工程的最新研究。总之,我们认为本综述阐述了碳纳米材料及其纳米复合材料的潜力和适用性,并提出了碳基纳米复合材料在生物医学应用中的未来应用方向。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52c8/10900039/cd76b933e95f/d3ra08946k-p5.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52c8/10900039/37b7c7b30ece/d3ra08946k-p1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52c8/10900039/cda9e0728d00/d3ra08946k-p2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52c8/10900039/e4d8a4c8511d/d3ra08946k-p3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52c8/10900039/763d17d81f4d/d3ra08946k-p4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52c8/10900039/cd76b933e95f/d3ra08946k-p5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52c8/10900039/464d0ddf73c4/d3ra08946k-f1.jpg
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https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52c8/10900039/fbae5e3f40d5/d3ra08946k-f5.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/52c8/10900039/37b7c7b30ece/d3ra08946k-p1.jpg
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2
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Luminescence. 2023 May;38(5):518-526. doi: 10.1002/bio.4473. Epub 2023 Apr 16.
3
Nanomaterial-based biohybrid hydrogel in bioelectronics.
负载替莫唑胺的双功能化碳纳米结构的放射增敏特性
Beilstein J Nanotechnol. 2025 Feb 19;16:229-251. doi: 10.3762/bjnano.16.18. eCollection 2025.
4
Enhanced Piezoresistive Cryogel: MWCNT Nanocomposite-Based Wearable Sensors for Real-Time Human Gait and Exercise Monitoring.增强型压阻式冷冻凝胶:基于多壁碳纳米管纳米复合材料的可穿戴传感器用于实时人体步态和运动监测。
ACS Omega. 2025 Jan 30;10(5):4940-4951. doi: 10.1021/acsomega.4c10391. eCollection 2025 Feb 11.
5
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Bioengineering (Basel). 2024 Dec 3;11(12):1222. doi: 10.3390/bioengineering11121222.
6
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Nanomedicine (Lond). 2025 Feb;20(3):319-328. doi: 10.1080/17435889.2024.2443378. Epub 2024 Dec 24.
7
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ChemMedChem. 2025 Feb 1;20(3):e202400587. doi: 10.1002/cmdc.202400587. Epub 2024 Nov 20.
8
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J Fluoresc. 2024 Apr 16. doi: 10.1007/s10895-024-03728-3.
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Nano Converg. 2023 Feb 10;10(1):8. doi: 10.1186/s40580-023-00357-7.
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Anal Biochem. 2023 Feb 15;663:115015. doi: 10.1016/j.ab.2022.115015. Epub 2022 Dec 8.
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