Department of Rheumatology, Preventive Cardio-Rheuma Clinic, Diakonhjemmet Hospital, Oslo, Norway.
Scientific Institute for Quality of Healthcare, Radboud University Nijmegen, Nijmegen, The Netherlands.
Ann Rheum Dis. 2014 Jul;73(7):1284-8. doi: 10.1136/annrheumdis-2013-204792. Epub 2014 Mar 7.
As physicians we like to have evidence for making decisions about interventions to improve health. The evidence vacuum in the field of cardiovascular disease (CVD) prevention and clinical outcome in patients with rheumatoid arthritis (RA) has received vigorous attention in the recent literature. There is broad agreement that a patient with RA fulfilling the criteria established for the general population on CVD risk reduction should receive proven interventions, including smoking cessation, weight reduction, blood pressure control and lipid-lowering therapy. In accordance with these recommendations, and despite all the uncertainties about CVD treatment threshold, targets and outcome results in RA, we firmly advocate that CVD risk should be assessed and acted on in patients with RA as recommended for the general population, even while educational CVD-preventive programmes are being developed and hard CVD end point studies are undertaken in this patient population. The initial strategies for implementing CVD risk evaluation will necessarily be modest at first. There are several possible strategies for collection of data that can be incorporated into the daily routine during rheumatology consultations at outpatient clinics. We recommend starting with these simple procedures: 1. CVD risk factor recording and evaluation using risk calculators available for the general population 2. Referral of patients with high CVD risk to a primary care physician or a cardiologist skilled in this subject for follow-up 3. Providing information about excess CVD risk and how to modify it to the patients as major stakeholders.
作为医生,我们喜欢在做出干预决策以改善健康状况时,有证据作为依据。在心血管疾病 (CVD) 预防和类风湿关节炎 (RA) 患者临床结局领域,证据空白已经引起了近期文献的强烈关注。人们普遍认为,符合 CVD 风险降低标准的 RA 患者应接受已证实的干预措施,包括戒烟、减肥、控制血压和降脂治疗。根据这些建议,尽管在 RA 患者的 CVD 治疗阈值、目标和结局结果方面存在所有不确定性,我们仍坚决主张,应按照推荐的一般人群标准,对 RA 患者进行 CVD 风险评估和干预,即使正在为该患者人群制定心血管疾病预防教育计划并进行硬终点 CVD 研究。最初实施 CVD 风险评估的策略最初必然是适度的。有几种可能的数据收集策略可以在门诊风湿病咨询期间纳入日常工作。我们建议从以下简单的步骤开始:1. 使用适用于一般人群的风险计算器记录和评估 CVD 风险因素;2. 将 CVD 风险高的患者转介给初级保健医生或擅长该领域的心脏病专家进行随访;3. 向主要利益相关者(患者)提供有关 CVD 风险增加及其如何改变的信息。