Dirani Mohamed, Crowston Jonathan G, van Wijngaarden Peter
Centre for Eye Research Australia, Royal Victorian Eye and Ear Hospital, University of Melbourne, Melbourne, Australia.
Clin Exp Ophthalmol. 2014 Aug;42(6):574-81. doi: 10.1111/ceo.12306. Epub 2014 Apr 9.
Physical inactivity and sedentary behaviour have been identified as modifiable risk factors for diabetes. However, little is known of the associations between physical activity, sedentary behaviour and diabetic retinopathy. The development of diabetic retinopathy is associated with longer duration of diabetes, elevated blood pressure and poor glycaemic control. However these factors only explain a proportion of the risk of retinopathy in individuals with diabetes. Several studies have suggested a protective role for physical activity in diabetic retinopathy. Other work has shown that the time spent watching television is independently associated with abnormal retinal vascular signs. Limitations of the existing studies, such as the absence of objective measures of physical activity, a lack of sedentary behaviour measures, the inclusion of only those with type 1 diabetes and a lack of longitudinal data, make it difficult to draw firm conclusions about the strength of these associations.
身体活动不足和久坐行为已被确认为糖尿病的可改变风险因素。然而,关于身体活动、久坐行为与糖尿病视网膜病变之间的关联,人们知之甚少。糖尿病视网膜病变的发生与糖尿病病程延长、血压升高及血糖控制不佳有关。然而,这些因素仅能解释糖尿病患者中视网膜病变风险的一部分。多项研究表明身体活动对糖尿病视网膜病变具有保护作用。其他研究则显示,看电视的时间与视网膜血管异常体征独立相关。现有研究存在局限性,如缺乏身体活动的客观测量方法、缺少久坐行为测量指标、仅纳入1型糖尿病患者以及缺乏纵向数据,这使得难以就这些关联的强度得出确凿结论。