室温下，芳基炔烃在水中的纳米胶束中进行有氧氧化。
Aerobic oxidation in nanomicelles of aryl alkynes, in water at room temperature.
作者信息
Handa Sachin, Fennewald James C, Lipshutz Bruce H
机构信息
Department of Chemistry & Biochemistry, University of California, Santa Barbara, CA 93106 (USA).
出版信息
Angew Chem Int Ed Engl. 2014 Mar 24;53(13):3432-5. doi: 10.1002/anie.201310634. Epub 2014 Feb 24.
Abstract
On the basis of the far higher solubility of oxygen gas inside the hydrocarbon core of nanomicelles, metal and peroxide free aerobic oxidation of aryl alkynes to β-ketosulfones has been achieved in water at room temperature. Many examples are offered that illustrate broad functional group tolerance. The overall process is environmentally friendly, documented by the associated low E Factors.
摘要
基于纳米胶束烃核内氧气的溶解度高得多，在室温下于水中实现了芳基炔烃无金属和过氧化物的有氧氧化生成β-酮砜。给出了许多示例来说明其对广泛官能团的耐受性。整个过程对环境友好，相关的低E因子证明了这一点。
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